ANAHEIM -- The Angels saw Mike Trout, Shohei Ohtani, Justin Upton and José Iglesias each smack a solo homer against the Rangers, but it wasn’t enough in a 7-4 loss Wednesday in the series finale at Angel Stadium.

It marked the second straight game that the Angels hit at least three homers against the Rangers, and the third time overall this season. They had previously gone 2-0 in games in which they homered at least three times and 9-5 when they homered at least once.

“We had a lot of good at-bats,” manager Joe Maddon said. “We put the ball in play. We had opportunities to score other runs. But overall, I was pleased with the method.”

It was the second homer in as many days for Trout, who is off to a scorching start offensively. The three-time American League MVP jumped on a first-pitch sinker from right-hander Mike Foltynewicz in the first inning for his team-leading sixth blast of the year. 

The homer was notable because not only did it come on the first pitch, but it was an opposite-field shot amidst a season in which Trout has been pulling the ball more. It was his first homer to right field since Sept. 25, 2020, and only four of his last 41 homers have gone out to the opposite field.

Ohtani joined the action with a solo blast in the third on a 2-2 slider from Foltynewicz, just two pitches after he saw a near home run go foul down the right-field line. But Ohtani didn’t miss Foltynewicz’s slider and skied it high into the air and beyond the right-field fence for his fifth homer of the year.

Because of its 38-degree launch angle, Ohtani wasn’t sure it was going to go out and raced around the bases in 17.3 seconds, giving him the fastest home run trot in the Majors this season.

Including his time in Japan, it was the 100th homer of Ohtani’s professional career, and his 52nd in the Majors. Ohtani, though, told the Japanese media after the game that he didn’t even realize it was his 100th career blast.

“I hadn’t really even paid attention to it,” Ohtani said. “I’m just glad I was able to hit one today.”

Upton’s homer was also notable in the fourth, as he hit a low line drive down the left-field line off Foltynewicz that just cleared the wall and had an incredible exit velocity of 116.5 mph. It became the hardest-hit homer by an Angels player since Statcast was introduced in 2015, surpassing Trout’s 115.5 mph homer in Tuesday’s 6-2 win.

Upton has homered in three of his last four games, but he came out of the game in the ninth, replaced by Jose Rojas, after feeling some discomfort at the plate in the eighth. But fortunately, after meeting with head athletic trainer Adam Nevala, it's only a cramp for Upton and he's expected to be back in the lineup Thursday.

“Just a cramp in the leg,” Maddon said. “As of right now, Adam says he’s fine.”

The homers weren’t enough, however, as the bullpen struggled to hold the lead. Reliever Mike Mayers gave up four runs in the eighth, keyed by a walk to Joey Gallo, followed by a go-ahead three-run homer from Adolis García and a solo shot from Nate Lowe. Right-hander Junior Guerra also struggled in the ninth, allowing runs to score on a walk and a balk.

"The walk to Gallo was big, and then the pitch to García, he just hung a slider," Maddon said. "And then, of course, Lowe. But that was his spot right there, Gallo-García-Lowe, but it just didn't work out."

Iglesias' first homer with the Angels came in the ninth off Rangers closer Ian Kennedy on a 1-0 fastball. Albert Pujols and Luis Rengifo also hit the ball hard off Kennedy but had nothing to show for it. 

“In that last inning, we hit four balls well,” Maddon said. “I thought it was a pretty good day. They had pretty good pitching. Foltynewicz pitched well. Their bullpen is very good. I thought we had some pretty good at-bats."