ST. PETERSBURG -- Wade Miley gave up three runs in six innings in his Astros debut, including a two-run homer by Austin Meadows in the third inning that proved to be the difference in a 3-1 loss to the Rays in Sunday’s series finale at Tropicana Field.

Rays starter Yonny Chirinos held the Astros to one run and two hits and struck out six batters in seven innings. He retired 20 of the 22 batters he faced, allowing a solo homer to Jake Marisnick in the third inning and an infield hit by Marisnick in the sixth.

After winning Thursday’s season opener, the Astros dropped three in a row to the Rays to fall to 9-18 all-time at Tropicana Field.The Astros, who welcomed shortstop Carlos Correa to the lineup Sunday after he had missed the first three games (neck), scored four runs in those three losses.

Miley, signed to a one-year, $4.5 million contract in February, gave up three runs in six innings and struck out four batters. He threw 60 of his 87 pitches for strikes.