"He's pretty sore," Giants manager Bruce Bochy said. "That calf swelled up pretty good when he got hit."
Bochy said Crawford's injured left oblique, which accounted for his previous absence, tightened up toward the end of the game.
"But the calf is the issue," Bochy said.
Ehire Adrianza replaced Crawford at shortstop and batted ninth in San Francisco's order -- one spot behind left-hander Madison Bumgarner. Typically, Bochy avoids batting a starting pitcher eighth. Until Tuesday, he did this just twice since his Giants' tenure began in 2007. Tim Lincecum hit ahead of Andres Torres in a 2010 game against Arizona and Bumgarner preceded Emmanuel Burriss in a 2012 encounter against St. Louis.
Adrianza entered Tuesday batting .169. Bumgarner, perhaps the most dangerous hitter among Major League pitchers, owned a .262 batting average with five home runs.
"This pretty much speaks for itself," Bochy said. "A.D.'s really struggling right now."