"This will make 30, so I'm kind of excited for that," Straily said.
In his last outing, Straily (1-2, 4.15 ERA) allowed three earned runs on four hits and three walks in 5 1/3 innings against the Pirates.
This will also be Straily's first time facing the Rays. Straily, who has 29 strikeouts in 26 innings this season, isn't really worried about the unfamiliarity with the free-swinging Tampa Bay lineup.
"It doesn't really matter," Straily said. "There's enough information out there on every hitter that we kind of know how we are going to match up."
Tampa Bay will send Matt Andriese (1-1, 3.86) to the hill for the series finale. The Rays are hoping for another strong outing from Andriese, who allowed three earned runs over seven innings on the road against the Blue Jays in his last outing, striking out four and walking three.
It was Andriese's longest outing since throwing a two-hit complete game against Oakland on May 14, 2016.
"That's all I try to do every time out," Andriese said. "Go out there, give our team a chance to win. If the starters can go deep in the game, the bullpen can stay fresh. So I try to do that every time out."
Heading into the northern tour of the annual Citrus Series, the Rays' bullpen was tied with Seattle for third-most relief appearances (84) in the American League.
Andriese will be trying to string together his first back-to-back outings of seven innings or more since his first two starts of 2016.
"They're aggressive, [so I want to] keep my pitch count down to let me go deep in the game," Andriese said.
Things to know about this game
• Andriese is 1-0 with a 2.40 ERA in five career Interleague appearances, including one start, which came against Miami last season.
• Based on the exit velocities and launch angles of the batted balls against him this season, Straily has posted an expected opponents' batting average of just .162. That leads all starters with at least 50 batters faced, just ahead of Boston's Chris Sale.
• Entering Wednesday, the Rays had committed four errors in 13 home games at Tropicana Field this season. On the road, the team has 12 errors in 15 games.