Smith suffered a groin strain in April, though it wasn't considered serious and he missed four starts and was then eased back into the lineup.
Quentin -- who hit a two-run home run on Saturday in a victory over the Rockies -- had a single in the first inning on Sunday and then felt some pain in the groin area as he went first-to-third base on Jedd Gyorko's double.
Two innings later, and with runners on first and second base and no outs, Quentin hit a ball that turned into a 5-4-3 triple play, even though he beat the return throw to first base. The Rockies were awarded a triple play anyway after Smith was called for interference as he slide into second base.
Quentin eventually left the game as part of a double-switch in the bottom of the fourth.
He missed the first 39 games of the season after suffering a bone bruise to his left knee in a Spring Training game in March. He returned on May 13 and has four hits in his first 12 at-bats over five games since then.
The Padres have an off-day Monday before opening a two-game series against the Twins at Petco Park on Tuesday. There will likely be more information made available about Quentin then.