BOSTON -- Teoscar Hernández's season has been filled with ups and downs, from the Majors to the Minors and back. On Tuesday night at Fenway Park, he was on the upswing with a pesky performance against the Red Sox in the Blue Jays' 10-4 win.

The center fielder opened up the Blue Jays' scoring in the second inning with a mammoth three-run home run off Andrew Cashner. The 441-foot shot to center, as projected by Statcast, was the team's fifth-longest of the year and Hernandez's longest of the season. He has homered twice in nine games this month.

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"I just saw tonight that I'm hitting eighth, and that gave me the chance to see the way he pitched against my teammates, the righties," Hernandez said. "I was seeing that he was throwing a lot of changeups when he was behind the count -- he was using it a lot to righties. So I was looking for it in that at-bat, that count and he threw one over middle and I put a good swing on it."

Blue Jays manager Charlie Montoyo noticed an improvement in Hernandez's plate appearances, because he moved his hands higher up on the bat. This was Hernandez's second game of the season recording more than two-plus runs and three-plus RBIs.

"That was great for him to see him hit that," Montoyo said. "That was a big blow today, that home run that he hit."

The early run support helped pitcher Jacob Waguespack settle into his first Major League start. The Red Sox had recorded a run in the first inning, and Waguespack held them scoreless for the next three frames after Hernandez's home run.

"Any time you get run support and a big swing like that, it was amazing," Waguespack said. "Right after that, I kind of just got on a roll there and made some quick outs. That was a huge weight off my shoulders there."

Two innings after Hernandez's home run, he struck out swinging and still safely raced to first on a wild pitch. He didn't score in the fourth, but that didn't slow down his aggressiveness on the basepaths.

Hernandez reached first in the sixth inning after grounding into a forceout. Red Sox reliever Josh Taylor tried to pick off Hernandez, but he threw the ball away. Hernandez, who entered Tuesday's game with the Blue Jays' fastest sprint speed (29.1 feet per second), was quick on his feet to dash to third. When Taylor struggled with another wild pitch, Hernandez scored to give the Blue Jays a two-run lead.

"I tried to take advantage with every little thing that happened during the game," Hernandez said. "I struck out, [but] I knew I could make it to first. With me on first, we have a lot of chances to score more runs because of my speed. … Every chance I get to move one base, I go for it."

The Blue Jays optioned Hernandez to Triple-A on May 16 for 19 games. He returned on June 5, and has hit six homers in 21 games since then. As Hernandez vies for playing time in the outfield, he aims to make the most of the opportunity when he sees his name in the lineup.

"I try to stay really strong mentally and keep working," he said.

The Blue Jays are 6-8 against the Red Sox this season, sparked by some power hitting. They have connected on 25 home runs in 14 games and tallied a total of 88 runs. Justin Smoak hit his 15th home run of the year off Cashner in the sixth. Lourdes Gurriel Jr. hit two triples (finishing a home run shy of the cycle) and Billy McKinney added one as well off Heath Hembree.

Each Blue Jays player in the starting lineup had at least one hit on Tuesday, a feat achieved for the third time this season. They spoiled Cashner's debut with the Red Sox by scoring six runs in five innings off the veteran starting pitcher.

"We're swinging the bats good," Montoyo said. "If our pitching gives us a chance, we're going to win more games. Our approach at the plate's outstanding. Guys are swinging the bat good and playing good defense. It's up to the pitching, and today was good. Our pitching was really good today against a good lineup."

Waguespack, who was called up from Triple-A on Tuesday, gave the Blue Jays 4 2/3 innings in his third career outing. The rookie allowed four runs (including a home run to Xander Bogaerts) off six hits with three walks and two strikeouts. From the last out of the first inning through two outs in the fifth, Waguespack retired 11 of the 13 batters he faced.

"He was throwing strikes, he did a good job," Montoyo said. "He kept us in the game. I'm pleased with his start."

The Blue Jays are 3-3 in their last six games, and improved to 27-2 on the season when leading after six innings.