Orioles Roster & Staff
Transactions
| Date | Transaction |
| 05/15/25 | Baltimore Orioles optioned RHP Chayce McDermott to Norfolk Tides. |
| 05/14/25 | Baltimore Orioles activated 3B Ramón Urías from the 10-day injured list. |
| 05/14/25 | Baltimore Orioles signed free agent RHP Asael Arias to a minor league contract. |
| 05/14/25 | Baltimore Orioles optioned LF Dylan Carlson to Norfolk Tides. |
| 05/14/25 | Baltimore Orioles recalled RHP Chayce McDermott from Norfolk Tides. |
| 05/11/25 | Baltimore Orioles activated RHP Zach Eflin from the 15-day injured list. |
| 05/11/25 | Baltimore Orioles optioned LHP Trevor Rogers to Norfolk Tides. |
| 05/11/25 | Baltimore Orioles optioned RHP Colin Selby to Norfolk Tides. |
| 05/10/25 | Baltimore Orioles sent RHP Matt Bowman outright to Norfolk Tides. |
| 05/09/25 | Baltimore Orioles activated RF Tyler O'Neill from the 10-day injured list. |
| 05/09/25 | Baltimore Orioles sent LHP Walter Pennington outright to Norfolk Tides. |
| 05/09/25 | Baltimore Orioles optioned 3B Coby Mayo to Norfolk Tides. |
| 05/08/25 | Baltimore Orioles sent RHP Andrew Kittredge on a rehab assignment to Norfolk Tides. |
| 05/08/25 | Baltimore Orioles designated RHP Matt Bowman for assignment. |
| 05/08/25 | Seattle Mariners traded RHP Luis F. Castillo to Baltimore Orioles for cash. |
| 05/08/25 | Baltimore Orioles recalled RHP Colin Selby from Norfolk Tides. |
| 05/07/25 | Baltimore Orioles designated LHP Walter Pennington for assignment. |
| 05/07/25 | Baltimore Orioles signed free agent RHP Ezequiel Sosa to a minor league contract. |
| 05/06/25 | Baltimore Orioles sent RF Tyler O'Neill on a rehab assignment to Norfolk Tides. |
| 05/04/25 | Baltimore Orioles sent RHP Andrew Kittredge on a rehab assignment to Aberdeen IronBirds. |
| 05/04/25 | Baltimore Orioles activated RHP Chayce McDermott from the 15-day injured list. |
| 05/04/25 | Baltimore Orioles sent RHP Zach Eflin on a rehab assignment to Aberdeen IronBirds. |
| 05/04/25 | Baltimore Orioles optioned RHP Chayce McDermott to Norfolk Tides. |
| 05/03/25 | Baltimore Orioles sent RHP Chayce McDermott on a rehab assignment to Norfolk Tides. |
| 05/03/25 | Baltimore Orioles placed 3B Ramón Urías on the 10-day injured list retroactive to May 1, 2025. Right hamstring strain. |
| 05/03/25 | Baltimore Orioles recalled 3B Coby Mayo from Norfolk Tides. |