Pirates Roster & Staff
Transactions
| Date | Transaction |
| 04/26/12 | Pittsburgh Pirates optioned Jared Hughes to Indianapolis Indians. |
| 04/25/12 | Pittsburgh Pirates recalled Jared Hughes from Indianapolis Indians. |
| 04/21/12 | Pittsburgh Pirates activated RHP A.J. Burnett from the 15-day disabled list. |
| 04/21/12 | Pittsburgh Pirates optioned Jared Hughes to Indianapolis Indians. |
| 04/18/12 | Pittsburgh Pirates recalled Brad Lincoln from Indianapolis Indians. |
| 04/18/12 | Pittsburgh Pirates placed RHP Jeff Karstens on the 15-day disabled list. Sore right shoulder. |
| 04/14/12 | Pittsburgh Pirates optioned Matt Hague to Indianapolis Indians. |
| 04/14/12 | Pittsburgh Pirates activated RHP Charlie Morton from the 15-day disabled list. |
| 04/09/12 | Pittsburgh Pirates signed free agent RHP Rick van den Hurk to a minor league contract. |
| 04/07/12 | Pittsburgh Pirates traded LHP Brian Tallet to San Diego Padres. |
| 04/04/12 | Pittsburgh Pirates activated RHP Juan Cruz. |
| 04/04/12 | Pittsburgh Pirates placed RHP A.J. Burnett on the 15-day disabled list retroactive to March 26, 2012. Fractured right orbital bone. |
| 04/04/12 | Pittsburgh Pirates placed RHP Charlie Morton on the 15-day disabled list retroactive to March 29, 2012. Recovering from October 2011 right hip surgery. |
| 04/04/12 | Pittsburgh Pirates selected the contract of Juan Cruz from Indianapolis Indians. |
| 04/04/12 | Chris Leroux roster status changed by Pittsburgh Pirates. |
| 04/03/12 | Pittsburgh Pirates optioned LHP Daniel Moskos to Indianapolis Indians. |
| 04/01/12 | Pittsburgh Pirates optioned Brad Lincoln to Indianapolis Indians. |
| 04/01/12 | Pittsburgh Pirates optioned Daniel McCutchen to Indianapolis Indians. |
| 04/01/12 | OF Andrew Lambo assigned to Pittsburgh Pirates. |