Players to homer twice in their regular-season debuts

So far in 2026, we’ve had not one but TWO players homer twice in their regular-season debuts.

On Thursday, Chase DeLauter homered twice in his regular-season debut -- the Guardians outfielder made his MLB debut in the 2025 postseason, but Opening Day marked his first regular-season game. Just five days later, Arizona’s Jose Fernandez had a debut for the ages with two dingers, including the go-ahead three-run shot in the bottom of the eighth.

According to the Elias Sports Bureau, DeLauter and Fernandez became the seventh and eighth players, respectively, to hit multiple home runs in their regular-season debuts. Here are the players who form that exclusive club.

Jose Fernandez, D-backs, March 31, 2026
Fernandez was called into MLB action just five days into the regular season after the D-backs placed Pavin Smith on the injured list. He made the most of his opportunity, hitting a pair of home runs against the Tigers, including the game-winning three-run home run off Kenley Jansen in the eighth inning. Fernandez, the D-backs’ No. 27 prospect (per MLB Pipeline) entering the season, only had one career multihomer game in pro ball, back in 2024 for High-A Hillsboro, before his MLB debut.

Chase DeLauter, Guardians, March 26, 2026
After seeing his first action during the 2025 American League Wild Card Series, the Guardians’ No. 2 prospect met the moment on Opening Day. DeLauter slugged a pair of home runs in his first and last at-bats of the night against the Mariners at T-Mobile Park, becoming only the 12th player to homer for the Guardians in a regular-season debut -- and the only one in franchise history to do so twice. DeLauter didn’t stop there: He went on to homer in each of his next two games, becoming one of only four players to homer in their first three career regular-season contests.

Trevor Story, Rockies, April 4, 2016
Perhaps no player can say they got off to as hot a start as Story did as a Rockies rookie back in 2016. The young shortstop went yard twice on Opening Day at Chase Field, hitting both homers off likely future Hall of Famer Zack Greinke, including a three-run clout for his first Major League hit. Story went on to homer in his second, third and fourth games, the longest streak to begin a career in MLB history. He even went deep twice in Game No. 4, giving him six homers in his first four contests.

J.P. Arencibia, Blue Jays, Aug. 7, 2010
Arencibia crushed 80 home runs in six MLB seasons, and that power was immediately on display in his debut. The Blue Jays catcher homered against Tampa Bay’s James Shields on the first pitch of his first at-bat, doubled his next time up, singled in his third trip to the plate and crushed a solo homer in his fourth plate appearance. Arencibia’s four-hit, two-homer effort was the main event in a wild 17-11 Blue Jays win that saw Toronto slug eight home runs.

Mark Quinn, Royals, Sept. 14, 1999
Quinn made his debut at designated hitter for the second game of a September doubleheader against the Angels at Kauffman Stadium, and he sure made his mark. After a double to lead off the bottom of the fourth, Quinn slugged a two-run homer in the sixth and another to take the lead in the eighth. It was an impressive start for Quinn, and he had another multihomer game -- one of five in his career -- just six days later.

Bert Campaneris, Kansas City Athletics, July 23, 1964
Campaneris’ strong debut kicked off an excellent career that included six All-Star appearances and three World Series titles. In his debut against the Twins, Campaneris hit a pair of home runs -- both against Jim Kaat -- and singled, walked and stole a base. Campaneris wasn’t necessarily known as a power hitter, only hitting 79 home runs in parts of 19 MLB seasons, and this was just one of three career multihomer efforts.

Bob Nieman, St. Louis Browns, Sept. 14, 1951
Nieman’s debut was a late bright spot for a Browns team that finished last in the American League with a 52-102 record. He remains the only player to homer in his first two MLB at-bats, homering twice off Mickey McDermott of the Red Sox at Fenway Park. Nieman went on to a 12-year MLB career, finishing seventh in AL MVP voting during a standout 1956 with the White Sox and Orioles.

Charlie Reilly, Columbus Solons, Oct. 9, 1889
Reilly only hit 17 home runs in parts of eight seasons, making this achievement all the more remarkable. Reilly’s pair of home runs were a leading cause in a 10-6 win over the Athletics for the Columbus Solons, who started play that season in the American Association before folding after 1891.