ANAHEIM -- A day after outlasting the Angels in a 16-inning classic that exhausted their bullpen, the Orioles made a flurry of roster moves Friday that touched nearly every corner of their pitching staff. They were both related and unrelated to Thursday night’s classic, and had Baltimore scrambling to rearrange its pitching picture as late as an hour prior to first pitch Friday.

Here is a breakdown of what transpired Friday and how it affects the club going forward.

John Means placed on injured list

The issue with Baltimore’s lone All-Star is a left biceps strain, similar to the left shoulder issue that landed him briefly on the IL in June. Orioles manager Brandon Hyde said Means first felt discomfort in his last start, a 3 1/3 inning slog in Arizona on Wednesday. Two days later, Means tested his arm with a series of drills on the outfield grass at Angel Stadium. Shortly after completing that session, Means was placed on the IL with what Hyde characterized as a minor issue.

“It all happened in the last 15 minutes,” Hyde said. “I’m really relying on our medical people and they’re really not concerned about it at all. I don’t think there are any red flags there. It’s his rookie year, even though he has a track record of [durability], the intensity level is different here. I think he’s still getting used to the Major League grind.”

By far the Orioles’ most valuable pitcher this season, the rookie Means is 8-6 with a 3.12 ERA and 3.4 bWAR in 21 games (17 starts) in 2019. Hyde said the club did not immediately know how it would fill his spot in the rotation, though Gabriel Ynoa, or perhaps even Dan Straily, seem to qualify as early candidates.

Means had been in line to start Monday in San Diego. His IL stint is backdated to July 25.

Dillon Tate, Evan Phillips promoted; Tanner Scott optioned to Triple-A Norfolk

The series of moves directly related to last night’s marathon now creates the first Major League opportunity for Tate, the club’s No. 17 ranked prospect per MLB Pipeline. Acquired from the Yankees in last July’s trade that sent Zack Britton to the Bronx, Tate, 25, is the former No. 4 overall pick in the 2015 Draft. The Yankees acquired him for Carlos Beltran the following summer before flipping him to Baltimore, where Tate, primarily a starter in his career, converted into a full-time reliever this year.

It translated to a drastically improved run for Tate at Double-A Bowie compared to his first look there last summer. He’d pitched to a 3.48 ERA over 17 appearances this year, all but two of those coming in a relief role. In 2018, Tate went 2-3 with a 5.75 ERA in seven games at Bowie, all starts. He is a candidate to provide multi-inning appearances for the Orioles; 10 of Tate’s 16 at Bowie were of that variety.

“The bullpen seems like the best place for me right now,” Tate said. “I felt like there wasn’t as much time for me to think in the bullpen. It’s just a 'go' type of mentality. Starting, I think a little bit too much. The bullpen is more suited for me.”

A Southern California native, Tate grew up going to Angels games and said he’ll have several family members and friends in attendance this weekend.

“I remember sitting in left field in that first little section, so it’s pretty cool to be on the field now.”

For Phillips, this is his sixth separate stint with the Orioles this season. The right-hander made an appearance in Friday's win over the Angels, allowing one run on a solo shot and striking out two in his inning of work. Phillips owns a 7.85 ERA in 17 games and 18 1/3 innings this season.

Scott was the obvious choice to be sent to Norfolk after blowing a three-run lead in the 15th inning late Thursday.

Nate Karns DFA

On top of all that, the Orioles also parted ways their lone free agent acquisition this winter, designating veteran right-hander Nate Karns for assignment. Karns, 31, made four scoreless appearances before being sidelined in early April with right forearm tightness, embarking on six separate rehab assignments in the three-plus months since.

A veteran of parts of six big league seasons, Karns owns a career 16-12 record and 4.30 ERA with the Nationals, Rays, Mariners, Royals and Orioles. He’s made just 13 appearances since 2017 due to lingering arm trouble.

When a player's contract is designated for assignment -- often abbreviated "DFA" -- that player is immediately removed from his club's 40-man roster, and 25-man roster if he was on that as well. Within seven days of the transaction (it was previously 10 days), the player must either be traded, released or placed on irrevocable outright waivers. Karns had been on the 60-day IL, so his 40-man roster spot was already cleared.