CHICAGO -- Miguel Gonzalez's five-start home win streak came to an end and the White Sox losing streak extended to six straight as the Padres claimed a 6-3 victory during Interleague action Friday night at Guaranteed Rate Field. The White Sox have been outscored 34-18 during this stretch.

Gonzalez (3-3) allowed five runs on eight hits over five innings, striking out two and walking four. He also yielded home runs to Matthew Szczur on the first pitch of the game and to Austin Hedges with two outs in the fifth. Hedges finished with two extra-base hits and three RBIs.

"I felt like every inning they had someone on," said Gonzalez, who has only walked 14 over 44 2/3 innings. "Just had to make pitches and it didn't go my way. I didn't have my best stuff tonight. You've just got to move on and work for the next one and get better in between starts."

Leury Garcia powered the White Sox to stay close with his first career multi-home-run effort. Garcia, starting at shortstop in place of Tim Anderson, went deep in the third following a Willy Garcia single and then launched a solo shot in the seventh to end Jhoulys Chacin's evening. The trio of Leury, Willy and Avisail Garcia knocked out six of the team's eight hits.

• Anderson given weekend off for funeral

Chacin allowed three runs on seven hits over 6 1/3 innings, walking one and striking out five. William Myers added an insurance run in the ninth inning with his ninth home run of the season.

MOMENTS THAT MATTERED

Doubling his pleasure: Hedges gave the Padres a cushion they wouldn't relinquish with a two-run double off Gonzalez with two outs in the third. The ball barely stayed fair and allowed Cory Spangenberg and Yangervis Solarte to score for a 3-0 Padres' advantage. Solarte barely beat the throw home with a great slide.

Looking and sitting: Trailing 5-2 following a two-run top of the fifth inning for San Diego, the White Sox fought back quickly against Chacin in the bottom half via singles from Leury Garcia and Avisail Garcia. Todd Frazier stood as the potential tying run with two outs in the frame, but he took a called third strike to end the rally.

QUOTABLE

"He battled well all day. Honestly, the last home run was on me. He shouldn't have been out there facing [Leury Garcia]. It was one of the worst decisions I've made. He should've been out by that point in time, but he got an easy out before and had a relatively easy inning in the sixth. He was outstanding." -- Padres manager Andy Green, on Chacin

"We're not too far back. I understand that it's tough when we're not winning ballgames, but we've had a lot of them that have been close. We've got to keep going out there, keep grinding. Things are going to start going our way. We have a good team, good ballclub. We can't put our heads down. Just keep working." -- Gonzalez, on the team's six-game losing streak

• Solarte flies into the stands, emerging with a fan's cap

SOUND SMART WITH YOUR FRIENDS

In his first game in Chicago since the Cubs traded him to the Padres on Monday, Szczur smacked the opening pitch for a home run. It was his first homer of the season and ninth of his career. It was also the Padres' third first-inning, leadoff home run of the year. Szczur hit a career-high five homers last season with the Cubs.

"I was just trying to get a good pitch to hit, and it happened to be the first pitch," Szczur said. "I'm aggressive, and these guys here push aggressiveness, so it's good for me."

"Two-seam fastball, right down the middle," Gonzalez said. "As a pitcher you want to get ahead, first pitch in the game and he got a piece of it. You tip your hat to him. You move on from there."

UPON FURTHER REVIEW

A bunt by Allen Cordoba originally was ruled an out at first, from Gonzalez to Jose Abreu, with one out and a runner on first in the fourth. But Green challenged the call and it was overturned by video replay, leaving runners at first and second with nobody out.

That call came moments after Hunter Renfroe's fly ball down the left-field line was changed from his sixth home run to a foul ball. There was no challenge used in this situation, with the umpires getting together and overturning it on the field.

GETTING THINGS ON TRACK

White Sox manager Rick Renteria met with his coaches for 20 minutes after the game, trying to correct some issues moving into Saturday's contest.

"We had to take care of a few things. We're always making corrections," Renteria said. "We were making some corrections, some things we need to work on and that was basically it. Actually some other defensive work that we're going to do, specialized and a little bit more detailed."

WHAT'S NEXT

Padres: Right-hander Trevor Cahill (3-2, 3.06 ERA) returns to Chicago after pitching with the Cubs during the last two seasons. He is 3-0 with a 0.49 ERA at home but 0-2 with a 5.82 ERA on the road. First pitch Saturday is at 4:10 p.m. PT.

White Sox:Dylan Covey (0-3, 8.28) makes his sixth start in search of career victory No. 1 and his second outing at Guaranteed Rate Field. The right-hander gave up six runs on 10 hits over four innings in his last loss to the Orioles. The White Sox also are giving away the much anticipated Ken "Hawk" Harrelson alarm clock to the first 20,000 Saturday, with a 6:10 p.m. CT first pitch.

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