The Question: Which is the weekend's best Interleague matchup?

The second weekend of Interleague Play 2012 brings a huge slate of interesting games: The annual Subway Series battle is the headliner but far from the only one.

The impressive Indians take on the world champion Cardinals, the surprising first-place Orioles play the surprising last-place Phillies, the Nationals meet the Red Sox, the Tigers play the Reds, the Blue Jays play the Braves, and the Marlins-Rays series matches a pair of contending teams.

That’s seven series pitting either two contenders or a contender and a team expected to be one.

So we want to know, out of this intriguing weekend, what’s the one can’t-miss series?