All-Time Roster
The following players have appeared in the Arizona Fall League since the league was established in 1992. The listed organization was the one the player was with when he played in the AFL.
S
| Player | Organization / AFL Team / Year |
|---|---|
| Sabato, Aaron | Twins Glendale 2023 |
| Sabel, Eric | D-backs Scottsdale 1996 |
| Sabol, Blake | Pirates Surprise 2022 |
| Sabrowski, Eric | Guardians Peoria 2023 |
| Sackinsky, Brian | Orioles Scottsdale 1994; Phoenix 1996 |
| Sadler, Aldren | Brewers Sun Cities 1996 |
| Sadler, Billy | Giants Scottsdale 2006 |
| Sadler, Donnie | Red Sox Mesa 1996 |
| Sadler, Ray | Cubs Mesa 2002 |
| Sadzeck, Connor | Rangers Surprise 2015 |
| Saenz, Chris | Brewers Peoria Jav 2005 |
| Saenz, Dustin | Nationals Salt River 2024 |
| Saenz, Jason | Mets Mesa 2001 |
| Saenz, Olmedo | White Sox Mesa 1993 |
| Saffer, Jon | Expos Phoenix 1995 |
| Saggese, Thomas | Cardinals Glendale 2024 |
| Sagmoen, Marc | Rangers Mesa 1994; Tempe 1996; Scottsdale 1997 |
| Saipe, Mike | Rockies Scottsdale 1997 |
| Sak, James | Padres Sun Cities 1997 |
| Saladin, Darlin | Cardinals Glendale 2025 |
| Saladino, Tyler | White Sox Mesa 2011 |
| Salas, Ethan | Padres Peoria 2024 |
| Salas, Jose | Marlins Mesa 2022 |
| Salazar, Jeff | Rockies Peoria Jav 2005 |
| Salcedo, Edward | Braves Phoenix 2012 / Braves Peoria 2014 |
| Salinas, Royber | Athletics Mesa 2023 |
| Salome, Angel | Brewers Peoria Jav 2008 |
| Saltalamacchia, Jarrod | Braves Phoenix 2005; Peoria Jav2006 |
| Samaniego, Tyler | Pirates Salt River 2023 |
| Sammons, Clint | Braves Peoria Jav 2007 |
| Sampen, Caleb | Rays Scottsdale 2021 |
| Sampson, Adrian | Pirates Scottsdale 2014 |
| Sampson, Benj | Twins Sun Cities 1997 |
| Sampson, Keyvius | Padres Peoria 2013 |
| Sanabia, Alex | Marlins Surprise 2011 |
| Sanabria, Carlos | Astros Peoria 2019 |
| Sanabria, Romeo | Padres Peoria 2024 |
| Sanburn, Nolan | White Sox Glendale 2016 |
| Sanches, Brian | Phillies Surprise 2005 |
| Sanchez, Aaron | Blue Jays Salt River 2013 |
| Sanchez, Ali | Mets Scottsdale 2018-19 |
| Sanchez, Angel | Pirates Scottsdale 2014 |
| Sanchez, Carlos | White Sox Salt River 2012 |
| Sanchez, Franklin | Mets Peoria 2022 |
| Sanchez, Freddy | Red Sox Grand Canyon 2001; Pirates Peoria Sag 2004 |
| Sanchez, Gaby | Marlins Peoria Jav 2006 |
| Sanchez, Gary | Yankees Surprise 2015 |
| Sanchez, Humberto | Tigers Mesa 2005 / Yankees Peoria Jav 2008 |
| Sanchez, Jadiel | Phillies Scottsdale 2023 |
| Sanchez, Juan | Giants Scottsdale 2025 |
| Sanchez, Miguel | Brewers Peoria 2018 |
| Sanchez, Salvador | White Sox Salt River 2012 |
| Sanchez, Tony | Pirates Mesa 2010 |
| Sanchez, Yolbert | White Sox Glendale 2021 |
| Sanders, Anthony | Blue Jays Phoenix 1997 |
| Sanders, Dave | White Sox Peoria 2002 |
| Sanders, Phoenix | Rays Peoria 2018 |
| Sanders, Tracy | Indians Tucson 1992 |
| Sandridge, Jayvien | Reds Surprise 2023 |
| Sands, Donny | Yankees Surprise 2019 |
| Sands, Jerry | Dodgers Phoenix 2010 |
| Sandusky, Scott | Expos Maryvale 2000 |
| Santana, Edgar | Pirates Surprise 2016 |
| Santana, Osmany | Indians Phoenix 2000 |
| Santana, Tyler | Cubs Mesa 2023 |
| Santander, Anthony | Orioles Salt River 2017 |
| Santangelo, Lou | Astros Mesa 2006 |
| Santiago, Andres | Dodgers Mesa 2012 |
| Santos, Adalberto | Pirates Scottsdale 2012 |
| Santos, Alex | Astros Surprise 2024 |
| Santos, Antonio | Rockies Salt River 2019 |
| Santos, Chad | Royals Peoria Jav 2003 |
| Santos, Gregory | Giants Scottsdale 2021 |
| Santos, Pedro | Athletics Mesa 2021 |
| Santos, Reid | Indians Peoria Jav 2006 |
| Santos, Sergio | D-backs Scottsdale 2003 / Blue Jays Scottsdale 2007 / Free agent Peo Jav 2009 |
| Santos, Winston | Rangers Surprise 2025 |
| Sappelt, Dave | Reds Peoria Sag 2010 |
| Sappington, Mark | Rays Mesa 2014 |
| Sardinas Luis, | Rangers Surprise 2012 |
| Sardinha, Bronson | Yankees Grand Canyon 2005 |
| Sardinha, Dane | Reds Scottsdale 2002, 2003 |
| Sarfate, Dennis | Brewers Scottsdale 2004, 2006 |
| Sarmiento, Elio | Rangers Surprise, Mesa 2011 |
| Sasaki, Shane | Rays Peoria 2023 |
| Sasser, Rob | Rangers Peoria 1998 / Tigers Scottsdale 1999 |
| Satin, Josh | Mets Mesa 2010 |
| Satre, Jason | Reds Chandler 1992 |
| Satterwhite, Cody | Mets Scottsdale 2013 / Tigers Peoria Jav 2009 |
| Sauer, Kelena | Blue Jays Glendale 2025 |
| Sauer, Matt | Yankees Mesa 2023 |
| Sauerbeck, Scott | Mets Grand Canyon 1997 |
| Saunders, Chris | Mets Tucson 1992; Chandler 1993; Peoria 1996 |
| Saunders, Tony | Marlins Tempe 1996 |
| Savery, Joseph | Phillies Peoria Sag 2007 |
| Sawatski, Jay | Twins Mesa 2006 |
| Saylor, Jamie | Astros Sun Cities 1997; Maryvale 1998 |
| Scahill, Rob | Rockies Salt River 2011 |
| Scalamandre, Rich | Cardinals Surprise 2005 |
| Scarpetta, Cody | Brewers Peoria 2011 |
| Scarsone, Steve | Orioles Scottsdale 1992 |
| Scavuzzo, Jacob | Dodgers Glendale 2015 |
| Schafer, Jordan | Braves Peoria Jav 2007 |
| Schafer, Logan | Brewers Surprise 2010; Peoria 2011 |
| Schall, Eugene | Phillies Tempe 1993 |
| Schebler, Scott | Dodgers Glendale 2014 |
| Scheffer, Aaron | Mariners Peoria 1998 |
| Scheid, Rich | Reds Chandler 1992 |
| Schenk, Neil | Rays Peoria Sag 2010 |
| Scheppers, Tanner | Rangers Surprise 2009 |
| Scherzer, Max | D-backs Scottsdale 2007, 2008 |
| Schierholtz, Nate | Giants Scottsdale 2007 |
| Schimpf, Tyler | Giants Scottsdale 2019 |
| Schlichting, Travis | Dodgers Surprise 2008; Peoria Jav 2009 |
| Schmidt, Jeff | Angels Tempe 1993, 1994, 1995 |
| Schmidt, Konrad | Diamondbacks Scottsdale 2010 |
| Schmidt, Nick | Padres Peoria 2011 |
| Schmitt, Eric | Yankees Grand Canyon 2004 |
| Schmoll, Eric | Dodgers Scottsdale 2004 |
| Schmoll, Steve | Mets Mesa 2006 |
| Schneider, Brian | Expos Phoenix 1999 |
| Schoeneweis, Scott | Angels Scottsdale 1997 |
| Scholl, Chris | Angels Scottsdale 2011 |
| Scholtens, Jesse | Padres Peoria 2021 |
| Schoop, Jonathan | Orioles Surprise 2013 / Orioles Mesa 2012 |
| Schrader, Clay | Orioles Mesa 2012 |
| Schrager, Tony | Red Sox Mesa DD 2003 |
| Schreiber, Brad | Rays Mesa 2015 |
| Schreiber, John | Tigers Mesa 2018 |
| Schreiber, Scott | Astros Surprise 2022 |
| Schrock, Max | Athletics Mesa 2016 |
| Schroder, Chris | Expos Peoria Jav 2003 / Nationals Peoria Sag 2005 |
| Schuerholz, Jonathan | Braves Phoenix 2005 |
| Schultz, Bo | D-backs Salt River 2013 |
| Schultz, Jaime | Rays Peoria 2014 |
| Schultz, Mike | Dodgers Scottsdale 2004, 2006 |
| Schulze, Brett | Phillies Surprise 2022 |
| Schumaker, Jared "Skip" | Cardinals Grand Canyon 2003 |
| Schwaab, Andrew | Yankees Scottsdale 2017 |
| Schwarber, Tom | Tigers Sun Cities 1992 |
| Schwarber, Kyle | Cubs Mesa 2016 |
| Schwartz, Garrison | Braves Scottsdale 2019 |
| Schwartz, Jeff | White Sox Grand Canyon 1992 |
| Schwartz, JT | Mets Glendale 2023 |
| Schwimer, Michael | Phillies Scottsdale 2009 |
| Scivicque, Kade | Braves Salt River 2016 |
| Sclafani, Joe | Astros Salt River 2014 |
| Scott, Christian | Mets Peoria 2022 |
| Scott, Luke | Indians Mesa DD 2003 |
| Scott, Robby | Red Sox Surprise 2014 |
| Scott, Stephen | Red Sox Scottsdale 2022 |
| Scott, Tanner | Orioles Peoria 2015-16 / Salt River 2017 |
| Scott, Tayler | Brewers Salt River 2016 |
| Scott II, Victor | Cardinals Scottsdale 2023 |
| Scribner, Evan | Padres Peoria Sag 2009 |
| Scrubb, Andre | Dodgers Glendale 2018 |
| Seabold, Connor | Phillies Scottsdale 2019 / Red Sox Scottsdale 2021 |
| Seager, Corey | Dodgers Glendale 2013, 2014 |
| Seagle, Chandler | Padres Peoria 2021 |
| Seay, Bobby | Devil Rays Maryvale 1999 |
| Sechrist, Xander | Twins Peoria 2025 |
| Secoda, Jason | White Sox Mesa 1999 |
| Seefried, Tate | Yankees Phoenix 1995 |
| Seestedt, Mike | Orioles Mesa SS 2003 |
| Sefcik, Kevin | Phillies Peoria 1994, 1996 |
| Segal, Alex | Braves Scottsdale 2022 |
| Segedin, Rob | Yankees Phoenix 2011 |
| Segovia, Zack | Phillies Peoria Sag 2006 |
| Seguignol, Fernando | Expos Sun Cities 1998 |
| Segura, Jean | Angels Scottsdale 2011 |
| Seibel, Phil | Mets Phoenix 2002 |
| Selby, Colin | Pirates Surprise 2022 |
| Self, Derek | Nationals Mesa 2014 |
| Self, Todd | Astros Scottsdale 2004 |
| Sellers, Jeff | Rockies Sun Cities 1994 |
| Sellers, Justin | Dodgers Peoria Jav 2009 |
| Sellinger, Jack | Marlins Mesa 2025 |
| Selman, Sam | Royals Peoria 2014 |
| Semien, Marcus | White Sox Glendale 2013 |
| Seminaris, Adam | Brewers Surprise 2023 |
| Senger, Hayden | Mets Salt River 2021 |
| Senreiso, Juan | Rangers Peoria Sag 2004 |
| Sensley, Steven | Yankees Glendale 2018 |
| Seo, Jae | Mets Mesa 2001 |
| Serafini, Dan | Twins Chandler 1994; Scottsdale 1996 |
| Seratelli, Anthony | Royals Surprise 2011 |
| Serrano, Jim | Expos Phx '99; Mary '00 / Royals Peo Jav '03 |
| Serven, Brian | Rockies Salt River 2019 |
| Serwa, Kenny | Tigers Scottsdale 2025 |
| Severino, Pedro | Nationals Mesa 2014 |
| Sewald, Paul | Mets Scottsdale 2014 |
| Sewell, Lance | Athletics Phoenix 2010 |
| Sexson, Richie | Indians Scottsdale 1996 |
| Sexton, Chris | Rockies Peoria 1996; Scottsdale 1997 |
| Sexton, Jeff | Indians Tempe 1995 |
| Shackelford, Brian | Royals Scottsdale 2002 / Reds Scottsdale 2003 |
| Shackelford, Kevin | Brewers Surprise 2013 |
| Shafer, Justin | Blue Jays Salt River 2015; Mesa 2016 |
| Shaffer, Richie | Rays Salt River 2013 / Rays Phoenix 2012 |
| Shanks, James | Royals Peoria Jav 2003 |
| Sharp, Sterling | Nationals Surprise 2019 |
| Shave, Jon | Rangers Phoenix 1992 |
| Shaver, Colton | Astros Peoria 2019 |
| Shaw, Bryan | Diamondbacks Scottsdale 2010 |
| Shaw, Chris | Giants Scottsdale 2017 |
| Shaw, Curtis | Pirates Grand Canyon 1997 |
| Shaw, Travis | Red Sox Surprise 2013 |
| Shawaryn, Mike | Red Sox Mesa 2018 |
| Shearn, Tom | Astros Phoenix 2001; Mesa 2002 |
| Sheehan, Emmet | Dodgers Glendale 2022 |
| Sheehan, Sam | Athletics Mesa 2018 |
| Sheets, Gavin | White Sox Glendale 2019 |
| Sheff, Chris | Marlins Mesa 1995 |
| Sheffield, Jordan | Dodgers Glendale 2018 |
| Sheffield, Justus | Yankees Scottsdale 2017 |
| Shell, Steven | Angels USA 2007 |
| Sheller, Walker | Royals Surprise 2018 |
| Shelton, Chris | Tigers Grand Canyon 2004 |
| Shelton, Matt | Dodgers Glendale 2014 |
| Shepherd, Chandler | Red Sox Scottsdale 2015 |
| Sherfy, Jimmie | D-backs Salt River 2014 |
| Sherriff, Ryan | Cardinals Glendale 2016 |
| Sherrill, George | Mariners Peoria Jav 2003 |
| Sherrod, Justin | Red Sox Scottsdale 2002 |
| Shibilo, Andy | Red Sox Scottsdale 2002 |
| Shields, Ben | Rockies Salt River 2025 |
| Shields, Jamie | Devil Rays Phoenix 2005 |
| Shields, Scott | Angels Grand Canyon 1999 |
| Shier, Peter | Orioles Mesa SS 2003 |
| Shim, Jun-Seok | Marlins Peoria 2024 |
| Shoemaker, Steve | Rockies Scottsdale 1997 |
| Shoppach, Kelly | Red Sox Mesa DD 2003 |
| Shore, Logan | Athletics Mesa 2017 |
| Short, Brandon | White Sox Mesa 2011 |
| Short, Zack | Cubs Mesa 2019 |
| Shortslef, Josh | Pirates Grand Canyon 2006 |
| Shouse, Brian | Pirates Phoenix 1992, 1995 / Orioles Phoenix 1996 |
| Shreve, Colby | Phillies Scottsdale 2011 / Peoria 2012 |
| Shreve, Ryan | Twins Glendale 2022 |
| Shuck, J.B. | Astros Peoria Jav 2010 |
| Shuey, Paul | Indians Tucson 1992; Scottsdale 1993 |
| Shumaker, Anthony | Phillies Grand Canyon 1997 / Sun Cities 1998 |
| Siani, Michael | Reds Surprise 2021 |
| Siani, Sammy | Pirates Scottsdale 2024 |
| Sides, Grant | Indians Peoria 2014 / Scottsdale 2015 |
| Siegrist, Kevin | Cardinals Surprise 2012 |
| Sikaras, Pete | D-backs Scottsdale 2003 |
| Sikkema, T.J. | Royals Surprise 2022 |
| Sikorski, Brian | Astros Sun Cities 1997 |
| Sikula, Arik | Blue Jays Mesa 2014 |
| Silva, Eric | Tigers Scottsdale 2024 |
| Silva, Rubi | Cubs Mesa 2012 |
| Silva, Ted | Rangers Tempe 1996 |
| Simcox, A.J. | Tigers Mesa 2017 |
| Simmons, (Donald) James | Athletics Phoenix 2007, 2009 |
| Simmons, Brian | White Sox Mesa 1997 |
| Simmons, James | Athletics Phoenix 2012 |
| Simmons, Shae | Braves Scottsdale 2013 |
| Simms, John | Nationals Salt River 2015 |
| Simokaitis, Joe | Cubs Mesa 2007 |
| Simon, Kyle | Phillies Peoria 2013 / Phillies Peoria 2012 |
| Simon, Randall | Braves Tempe 1996 |
| Simon, Ronny | Rays Mesa 2022 |
| Simonelli, Anthony | Royals Surprise 2024 |
| Simonitsch, Errol | Twins Mesa 2006 |
| Simons, Mitch | Twins Peoria 1995 |
| Simons, Zach | Tigers Mesa 2008 |
| Simpson, Allan | Mariners Peoria 2001 / Reds Mesa 2005 |
| Simpson, Jared | Nationals Scottsdale 2025 |
| Simpson, Josh | Marlins Mesa 2021 |
| Sims, Lucas | Braves Peoria 2015 |
| Sinacori, Chris | Dodgers Mesa 1993 |
| Sinclair, Jack | Nationals Scottsdale 2023 |
| Sing, Brandon | Cubs Mesa 2005 |
| Singer, Jeff | Phillies Scottsdale 2016 |
| Singleton, Chris | Yankees Grand Canyon 1998 |
| Singleton, Duane | Brewers Chandler 1993, 1994 |
| Singleton, Jonathan | Astros Mesa 2012 |
| Singleton, Steve | Twins Mesa 2009 |
| Sinisi, Vince | Padres Peoria Sag 2006 |
| Sinnard, Luke | Braves Glendale 2025 |
| Sipp, Tony | Indians Peoria Jav 2006 |
| Siri, Dalbert | Indians Glendale 2018 |
| Sisco, Chance | Orioles Peoria 2015 |
| Sisk, Brandon | Royals Surprise 2009, 2010 |
| Sisk, Evan | Twins Scottsdale 2021 |
| Sitton, Kraig | Rockies Salt River 2013 |
| Sitzman, Jay | Phillies Grand Canyon 2002 |
| Sizemore, Grady | Indians USA 2003 |
| Sizemore, Scott | Tigers Peoria Sag 2007; Peoria Jav 2009 |
| Skipworth, Kyle | Marlins Phoenix 2010; Surprise 2011 |
| Skole, Matt | Nationals Mesa 2013 / Nationals Salt River 2012 |
| Skrmetta, Matt | Padres Scottsdale 1998 |
| Skuse, Nick | Angels Scottsdale 1997 |
| Slack, Ryne | Rangers Surprise 2015 |
| Slama, Anthony | Twins Phoenix 2008 |
| Slania, Dan | Giants Scottsdale 2015 |
| Slaten, Doug | D-backs Phoenix 2005 |
| Slaten, Justin | Rangers Surprise 2023 |
| Slater, Austin | Giants Scottsdale 2015 |
| Slavik, Corey | Rockies Mesa 2004 |
| Slayden, Jeremy | Phillies Mesa 2008 |
| Sledge, Terrmel | Expos Maryvale 2002; USA 2003 |
| Slocum, Brian | Indians Mesa 2005 |
| Slowey, Kevin | Twins Mesa 2006 |
| Small, Aaron | Blue Jays Tucson 1992; Mesa 1995 |
| Smeltzer, Devin | Twins Salt River 2018 |
| Smetana, Steve | Red Sox Phoenix 1997 |
| Smit, Kyle | Cubs Mesa 2010 |
| Smith, Aidan | Rays Mesa 2025 |
| Smith, Alex | Yankees Scottsdale 2014 |
| Smith, Austin | Braves Scottsdale 2022 / Rockies Salt River 2025 |
| Smith, Blake | Dodgers Glendale 2014 |
| Smith, Bobby | Braves Sun Cities 1995, 1996; Grand Canyon 1997 |
| Smith, Burch | Padres Surprise 2014; Royals Surprise 2017 |
| Smith, Cade | Guardians Peoria 2022 |
| Smith, Cade | Yankees Mesa 2025 |
| Smith, Cam | Mariners Peoria 1998 |
| Smith, Carlton | Indians Peoria Sag 2009 |
| Smith, Carson | Mariners Peoria 2013 / Mariners Peoria 2012 |
| Smith, Casey | Angels Phoenix 2004 |
| Smith, Chad D. | Tigers Glendale 2014 |
| Smith, Chad | Marlins Salt River 2018 |
| Smith, Chris | Red Sox Peoria Sag 2005 |
| Smith, Corey | Indians Mesa DD 2003 / Padres Surprise 2005 |
| Smith, Dan | Rangers Scottsdale 1997 |
| Smith, D'Andre | Mets Glendale 2023 / Scottsdale 2025 |
| Smith, Dominic | Mets Salt River 2015 |
| Smith, Dylan | Tigers Salt River 2023 |
| Smith, Eric | Diamondbacks Salt River 2011, 2012 |
| Smith, Greg | D-backs Scottsdale 2007 |
| Smith, Hagen | White Sox Glendale 2025 |
| Smith, Jason | Cubs Mesa 2000 / Devil Rays Maryvale 2001 |
| Smith, Jordan | Indians Peoria 2014 |
| Smith, Kevan | White Sox Glendale 2014 |
| Smith, Kevin | Blue Jays Scottsdale 2019 |
| Smith, Mallex | Padres Surprise 2014 |
| Smith, Mark | Orioles Scottsdale 1992 |
| Smith, Matt A. | White Sox Mesa 2004 |
| Smith, Matt J. | Yankees Grand Canyon 2005 |
| Smith, Michael | Blue Jays Scottsdale 2001 |
| Smith, Myles | D-backs Salt River 2015 |
| Smith, Murphy | Athletics Phoenix 2011 |
| Smith, Nate | Angels Mesa 2014 |
| Smith, Ottis | Cubs Mesa 1994 |
| Smith, Pavin | D-backs Salt River 2018 |
| Smith, Russell | Brewers Glendale 2022 |
| Smith, Scott | Marlins Peoria 1997 |
| Smith, Shane | Brewers Surprise 2023 |
| Smith, Tanner | Orioles Peoria 2025 |
| Smith, Toby | Royals Sun Cities 1996 |
| Smith, Tyler | Mariners Peoria 2015 |
| Smith, Will | Dodgers Glendale 2017 |
| Smith Jr., Dwight | Blue Jays Mesa 2014 |
| Smith-Njigba, Canaan | Pirates Peoria 2021 |
| Smitherman, Steve | Reds Scottsdale 2003 |
| Smoak, Justin | Rangers Peoria Jav, Surprise 2008 |
| Snare, Ryan | Reds Grand Canyon 2001 |
| Snead, Esix | Cardinals Scottsdale 2000 |
| Snell, Ian | Pirates Peoria Sag 2005 |
| Snelton, D.J. | Giants Scottsdale 2017 |
| Snider, Travis | Blue Jays Scottsdale 2007 |
| Snodgress, Scott | White Sox Glendale 2014 |
| Snopek, Chris | White Sox Scottsdale 1994 |
| Snow, Bert | Athletics Phoenix 1999, 2002 |
| Snow, Forrest | Mariners Peoria 2011 |
| Snyder, Brad | Indians Mesa 2005; Surprise 2007 |
| Snyder, Brandon | Orioles Surprise 2008; Phoenix 2009 |
| Snyder, Chris | D-backs Scottsdale 2003 |
| Snyder, Earl | Mets Mesa 2001 |
| Snyder, John | White Sox Mesa 1997 |
| Snyder, Kyle | Royals Scottsdale 2001, 2002 |
| Snyder, Nick | Rangers Surprise 2019 |
| Sobkowiak, Scott | Braves Phoenix 2001 |
| Soderstrom, Steve | Giants Scottsdale 1993, 1995 |
| Sodowsky, Clint | Pirates Peoria 1996 |
| Sogard, Alex | Astros Peoria 2013 / Astros Mesa 2012 |
| Soler, Jorge | Cubs Mesa 2013 |
| Solesky, Chase | White Sox Glendale 2022 / Nationals Salt River 2024 |
| Solis, Sammy | Nationals Mesa 2013 / Nationals Scottsdale 2011 / Nationals Scottsdale 2010 |
| Sollmann, Steve | Brewers Mesa 2007 |
| Sommers, Drew | Rays Peoria 2023 |
| Somsen, Layne | Reds Peoria 2015 |
| Song, Seung | Expos Peoria Jav 2004 |
| Songster, Judd | Rockies Grand Canyon 2006 |
| Sonnier, Shawn | Royals Grand Canyon 2000 |
| Sopko, Andrew | Dodgers Glendale 2017 |
| Sorenson, Zach | Indians Phoenix 2000; Scottsdale 2001 |
| Soriano, Alfonso | Yankees Grand Canyon 1998 |
| Sosa, Edmundo | Cardinals Surprise 2017 |
| Sosa, Thomas | Orioles Peoria 2025 |
| Soto, Elliot | Marlins Mesa 2015 |
| Soto, Geovany | Cubs Mesa 2004 |
| Soto, Gregory | Tigers Mesa 2018 |
| Sousa, Bennett | White Sox Glendale 2019 |
| Souza Jr., Steven | Nationals Mesa 2013 |
| Span, Denard | Twins Grand Canyon 2005 |
| Spangenberg, Cory | Padres Peoria 2013 / Padres Peoria 2012 |
| Spann, Chad | Red Sox Peoria Jav 2006 |
| Sparks, Steve | Pirates Peoria 2000 |
| Sparks, Taylor | Reds Scottsdale 2017 |
| Spears, Nate | Cubs Mesa 2008 |
| Speer, David | Indians Mesa 2016 |
| Speier, Gabe | D-backs Salt River 2016 |
| Speier, Justin | Cubs Mesa 1997 |
| Speier, Ryan | Rockies Mesa 2004; Grand Canyon 2006 |
| Spence, Josh | Padres Peoria 2012 |
| Spencer, Corey | Red Sox Grand Canyon 2001 |
| Spencer, Sean | Mariners Peoria 1997 |
| Spencer, Shane | Yankees Mesa 1996 |
| Spiehs, R.D. | Giants Grand Canyon 2002 / Padres Peoria Jav 2004 |
| Spiers, Carson | Reds Surprise 2023 |
| Spitzbarth, Shea | Dodgers Glendale 2017 |
| Spivey, Junior | D-backs Scottsdale 1998 |
| Spoljaric, Paul | Blue Jays Scottsdale 1993 |
| Spraker, Graham | Blue Jays Scottsdale 2019 / Mesa 2021 |
| Spring, Matt | Rays Peoria Jav 2008 |
| Springer, George | Astros Mesa 2012 |
| Springer, Russ | Yankees Phoenix 1992 |
| Sprinkle, Jonathan | Astros Surprise 2022 |
| Spruill, Zeke | Braves Phoenix 2012 |
| Spurlin, Tyler | Brewers Salt River 2016 |
| Spurling, Chris | Pirates Peoria 2000; Phoenix 2002 |
| Squier, Scott | Marlins Salt River 2017 |
| Squires, Brett | Royals Surprise 2024 |
| Squires, Matt | Phillies Mesa DD 2003 |
| Srickland, Scott | Expos Phoenix 1999 |
| St. Clair, Cole | Dodgers Salt River 2011 |
| St. Pierre, Maxim | Tigers Maryvale 2001; Mesa 2002; Grand Canyon 2003 |
| Stadler, Fitz | Blue Jays Surprise 2023 |
| Stahl, Richard | Orioles Peoria Jav 2004 |
| Stahoviak, Scott | Twins Chandler 1994 |
| Stamets, Eric | Angels Mesa 2014 |
| Stanavich, Dale | Marlins Peoria 2023 |
| Stanbridge, Jason | Devil Rays Maryvale 2001 |
| Stanford, Jason | Indians Scottsdale 2001; USA 2003 |
| Stange, Dan | Diamondbacks Scottsdale 2010 |
| Stankiewicz, Drew | Phillies Glendale 2015 |
| Stankiewicz, Teddy | Red Sox Mesa 2018 |
| Stanley, Cody | Cardinals Surprise 2012 / Peoria 2014 |
| Stanley, Hunter | Guardians Peoria 2022 |
| Stansberry, Craig | Pirates Grand Canyon 2006 |
| Stanton, Mike | Marlins Mesa 2009 |
| Stanton, Tom | Mets Grand Canyon 1997 |
| Stark, Dennis | Mariners Peoria 1999 |
| Starling, Bubba | Royals Peoria 2014 / Surprise 2015 |
| Starr, Nick | Rangers Surprise 2022 |
| Startup, Will | Braves Peoria Jav 2006; Peoria Sag 2007 |
| Stassi, Max | Athletics Phoenix 2012 |
| Staton, T.J. | Pirates Mesa 1996 |
| Staumont, Josh | Royals Surprise 2016 |
| Stavinoha, Nick | Cardinals Peoria Sag 2006 |
| Stebens, Isaac | Red Sox Salt River 2025 |
| Steckenrider, Drew | Marlins Mesa 2016 |
| Steedley, Spencer | Twins Mesa 2009 |
| Steele, Justin | Cubs Mesa 2018 |
| Stefanski, Mike | Brewers Peoria 1994 |
| Steffek, Brian | Dodgers Scottsdale 2003 |
| Stein, Blake | Athletics Phoenix 1997 |
| Steinbaugh, Conor | Red Sox Mesa 2024 |
| Stem, Craig | Dodgers Glendale 2013 |
| Stemle, Steve | Cardinals Maryvale 2002 |
| Stenson, Dernell | Red Sox Grand Canyon 1998 / Reds Scottsdale 2003 |
| Stentz, Brent | Twins Phoenix 1998 |
| Stephan, Josh | Rangers Surprise 2024 |
| Stephen, Josh | Phillies Scottsdale 2019 |
| Stephenson, Brian | Cubs Mesa 1996, 1999 |
| Stephenson, Garrett | Orioles Scottsdale 1995 |
| Stephenson, Tyler | Reds Glendale 2019 |
| Stern, Adam | Braves Mesa SS 2003 |
| Stertzbach, Von | Angels Surprise 2007 |
| Stetter, Mitch | Brewers Scottsdale 2004; Peoria Jav 2005; Mesa 2007 |
| Stevens, Dave | Cubs Mesa 1993 |
| Stevens, Jeff | Indians Surprise 2007, USA 2007 |
| Stevens, Kevin | Yankees Mesa 2023 |
| Stevenson, Andrew | Nationals Glendale 2016 |
| Steverson, Todd | Blue Jays SC '94 / Tigers SC '95 / Padres SC '96 |
| Stewart, Caleb | Mets Scottsdale 2007 |
| Stewart, Christin | Tigers Salt River 2016 |
| Stewart, DJ | Orioles Peoria 2016 |
| Stewart, Ethan | Phillies Scottsdale 2014 |
| Stewart, Ian | Rockies Peoria Jav 2005 |
| Stewart, Josh | White Sox Peoria 2002 |
| Stewart, Paul | Brewers Maryvale 2001 |
| Stidham, Phil | Tigers Chandler 1993; Tempe 1994 |
| Still, Jon | Red Sox Mesa 2007 |
| Stiller, Erik | Indians Surprise 2008 |
| Stilson, John | Blue Jays Salt River 2012-13; Mesa 2016 |
| Stinnett, Jake | Cubs Mesa 2017 |
| Stinson, Josh | Mets Surprise 2009 |
| Stites, Matt | D-backs Salt River 2013 / Padres Peoria 2012 |
| Stocker, Kevin | Phillies Chandler 1992 |
| Stockman, Landon | Indians Peoria Jav 2004 |
| Stocks, Nick | Cardinals Phoenix 2001 |
| Stodolka, Mike | Royals Phoenix 2004 |
| Stoffel, Jason | Giants Scottsdale 2010 / Astros Salt River 2011 |
| Stohr, Tyler | Tigers Salt River 2011 |
| Stokes, Brian | Devil Rays Phoenix 2005 |
| Stokes, Jason | Marlins Peoria Sag 2003 |
| Stone, Adam | Yankees Mesa 2025 |
| Stone, Ricky | Dodgers Peoria 1997,1999; Scottsdale 1998 |
| Stoneburner, Davis | Rangers Surprise 2010 |
| Stoner, Tobi | Mets Peoria Sag 2008 |
| Stoops, Jim | Rockies Scottsdale 1998, Peoria 2000 |
| Stoppelman, Lee | Cardinals Salt River 2013 |
| Storen, Drew | Nationals Phoenix 2009 |
| Storey, Mickey | Athletics Phoenix 2009 |
| Storm, Justin | Marlins Peoria 2024 |
| Story, Trevor | Rockies Salt River 2014 |
| Stott, Bryson | Phillies Peoria 2021 |
| Stotts, J.T. | Athletics Phoenix 2002 / Mesa DD 2003 |
| Stout, Eric | Royals Surprise 2016 |
| Stovall, Darond | Expos Mesa 1995, 1996 |
| Stowers, Josh | Yankees Surprise 2019 / Orioles Mesa 2021 |
| Strait, Cody | Reds Phoenix 2006 |
| Strahan, Wyatt | Reds Scottsdale 2018 |
| Strange, Pat | Mets Mesa 2001 |
| Strasburg, Stephen | Nationals Phoenix 2009 |
| Stratton, Chris | Giants Scottsdale 2016 |
| Stratton, Robert | Mets Mesa 2001 |
| Strausborger, Ryan | Rangers Surprise 2011 |
| Street, Huston | Athletics Phoenix 2004 |
| Stroman, Marcus | Blue Jays Salt River 2013 |
| Strong, Jamal | Mariners Peoria 2002; Peoria Jav 2003 |
| Strong, Mike | Brewers Glendale 2014 |
| Strotman, Drew | Rays Salt River 2019 |
| Stuart, Baron | Yankees Mesa 2023 |
| Stuart, Champ | Mets Scottsdale 2016 |
| Stubbs, Garrett | Astros Glendale 2016 |
| Struck, Nick | Cubs Mesa 2012 |
| Stubbs, Drew | Reds Peoria Jav 2008 |
| Stull, Everett | Expos Mesa 1995 |
| Stults, Eric | Dodgers Peoria 2002; Scottsdale 2004 |
| Stumpf, Daniel | Royals Peoria 2014 |
| Stumpo, Mitchell | D-backs Salt River 2021 |
| Sturdevant, Tyler | Indians Surprise 2013 / Indians Phoenix 2011 |
| Sturtze, Tanyon | Athletics Sun Cities 1993; Mesa 1995 |
| Stynes, Chris | Blue Jays Sun Cities 1994 |
| Sublette, Ryan | Dodgers Glendale 2023 |
| Suero, Chris | Mets Scottsdale 2025 |
| Sues, Jeff | Pirates Scottsdale 2008 |
| Sugastey, Adrian | Giants Scottsdale 2022 |
| Suggs, Colby | Marlins Glendale 2013 |
| Sulbaran, J.C. | Royals Surprise 2012 |
| Sullivan, Brett | Rays Surprise 2017 |
| Sullivan, Cory | Rockies Mesa 2004 |
| Sullivan, Joseph | Astros Scottsdale 2025 |
| Sullivan, Mike | Red Sox Scottsdale 1994 |
| Sullivan, Scott | Reds Peoria 1994; Scottsdale 1996 |
| Sulser, Beau | Pirates Peoria 2019 |
| Sundstrom, Jared | Mariners Peoria 2024 |
| Susac, Andrew | Giants Scottsdale 2013 |
| Susac, Daniel | Athletics Mesa 2024 |
| Susdorf, Steve | Phillies Scottsdale 2009 |
| Sutko, Glenn | Reds Chandler 1992 |
| Sutton, Drew | Astros Scottsdale 2008 |
| Sutton, Larry | Royals Scottsdale 1994 |
| Suzuki, Kurt | Athletics Phoenix 2005 |
| Suzuki, Makato | Mariners Peoria 1995, 1996 |
| Svanson, Matt | Cardinals Glendale 2024 |
| Swagerty, Jordan | Cardinals Surprise 2010 |
| Swaggerty, Ben | Royals Surprise 2009 |
| Swan, Eriq | Dodgers Glendale 2024 |
| Swanson, Nic | Astros Surprise 2024 |
| Swartzbaugh, Dave | Cubs Grand Canyon 1992 |
| Swarzak, Anthony | Twins Phoenix 2007 |
| Sweeney, Brian | Mariners Peoria 2001 |
| Sweeney, Darnell | Dodgers Glendale 2014 |
| Sweeney, Mark | Cardinals Peoria 1995 |
| Sweeney, Mike | Royals Sun Cities 1996 |
| Sweeney, Ryan | White Sox Phoenix 2007 |
| Sweet, Devin | Mariners Peoria 2021 |
| Swift, Drew | Athletics Mesa 2024 |
| Swingle, Paul | Angels Scottsdale 1992; Tempe 1993 |
| Swisher, Nick | Athletics Mesa DD 2003 |
| Sylvester, Billy | Braves Mesa 2000 |
| Szczur, Matt | Cubs Mesa 2012 |
| Szuminski, Jason | Cubs Mesa SS 2003 |
| Szykowny, Charlie | Giants Scottsdale 2024 |