SAN FRANCISCO -- The Giants’ first experience with the new extra-innings rule was a forgettable one. 

After rallying to erase a five-run deficit and force extra innings, the Giants came undone in the 10th. Submariner Tyler Rogers surrendered six runs and manager Gabe Kapler compounded the trouble by mishandling a pitching change, resulting in a deflating 12-7 loss to the Padres on Thursday night at Oracle Park.

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With the game tied, 6-6, after nine innings, the Padres opened the 10th with Trent Grisham at second base as the automatic runner. Rogers, who struck out two in a scoreless ninth, came back out for his second inning of work, but he issued a leadoff walk to Manny Machado before yielding a go-ahead single to Tommy Pham.

Rogers subsequently hit Jurickson Profar to load the bases, setting up back-to-back RBI singles by Greg Garcia and Ty France and triggering a mound visit from pitching coach Andrew Bailey. Manager Gabe Kapler then tried to bring in Rico Garcia to face Austin Hedges, but he was denied a pitching change because Rogers was required to face at least one more batter following the visit from Bailey.

“That was just a mental screw-up on my part,” Kapler said. “I’ve been around the game for a long time, and I just had a lapse in memory.”

Rogers, who had retreated to the dugout, was forced to return to the mound and face Hedges, who brought in another run with a sacrifice bunt. Fernando Tatis Jr. later capped the Padres’ six-run inning with an RBI single off Garcia.

“Gabe is a standup guy,” said Rogers, who faced six batters in the 10th without recording an out. “When he makes a mistake, he’ll be the first one to say it. I told him, ‘It’s OK.’ Hopefully, if I would have just pitched a little better, he wouldn’t have had to do that.”

The blunder will raise questions about Kapler’s ability to manage a bullpen, which also came under scrutiny during his two-year tenure with the Phillies. In his first weekend in Philadelphia in 2018, a miscommunication between the dugout and the bullpen led Kapler to bring reliever Hoby Milner into a game without Milner having thrown a single warm-up pitch.

“I think the most important thing is just own it, take responsibility for it and don’t make the same mistake twice,” Kapler said.

It was a stinging end for the Giants, who came close to stunning the Padres for the second consecutive night after rallying for a 7-6 walk-off win on Wednesday.

The Giants entered the bottom of the seventh trailing, 6-1, but they came alive against the Padres’ bullpen, scoring three runs against Luis Perdomo. They added two more in the eighth on Mike Yastrzemski’s RBI triple and Donovan Solano ’s game-tying sacrifice fly off Emilio Pagán.

Solano finished 4-for-5 with three doubles and two RBIs, raising his batting average to .500 (10-for-20) on the season. He has driven in nine runs over his first six games, tied with the Braves’ Dansby Swanson for the most in the National League.

Wilmer Flores led off the ninth with a single, but Pierce Johnson retired Mauricio Dubón, Tyler Heineman and Steven Duggar to force extra innings for the first time at Oracle Park this year. Duggar opened the bottom of the 10th on second base and scored on a groundout by Alex Dickerson, but David Bednar struck out Darin Ruf swinging to end the game.

“Unfortunately, it didn’t work out great for us tonight,” said first baseman Brandon Belt, who drew three walks in his season debut with the Giants. “I think because of the way this season is, it’s probably for the best that we do something to speed up the game going into extra innings right now. Hopefully, in the future we can kind of work it out to our advantage.”