SAN DIEGO -- Hunter Renfroe made a statement in his return to the Padres’ lineup Tuesday night. The only problem? His two homers off D-backs starter Zack Greinke were as many as Greinke hit himself.

Renfroe went deep twice in the Padres’ 8-5 loss to Arizona at Petco Park, a game in which San Diego pitchers surrendered five home runs, including two from Greinke. With consecutive losses to the D-backs, the Padres fell back to .500 after a thrilling season-opening series victory over the Giants.

The game wasn’t without its share of controversy. Manager Andy Green was tossed in the sixth inning after a strange play in which Manny Machado was ruled out for interference on a dropped popup. A batter later, Renfroe demolished his second homer of the night, turning the chorus of boos at Petco Park into lively cheers.

It was a laser home run off the facing of the Western Metal Building, leaving Renfroe’s bat at 111 mph, and it offered a stark reminder of Renfroe's capabilities. He has spent the early part of the season as a useful bench bat, with Wil Myers and Franmil Reyes getting regular starts in the outfield corners.

“Got to be ready when I’m called on, make sure I’m in the right spot, in the right peace of mind,” Renfroe said. “I just do what I do, do everything 100 percent and help the team to win.”

A season ago, Renfroe was, arguably, the Padres’ best hitter. He posted an .805 OPS with a team-high 26 homers and significantly improved his approach with two strikes.

Renfroe’s first homer came on a 2-2 curveball from Greinke in the bottom of the first. He crushed it into the home bullpen, giving the Padres a 2-0 lead.

“He’s a great competitor,” Green said of Renfroe. “Always has been. Loves big moments, thrives in them. Great swings tonight.”

If anything, Renfroe’s big night only makes Green’s outfield decisions harder moving forward. Myers came off the bench and homered, as well, on Tuesday. Reyes is off to a slow start, numbers-wise, but he’s scorching the ball, too.

“All those guys are doing some nice things,” Green said. “... Those guys make it tough every day to decide who is out there. The message to every one of them is: One of you is going to have a huge at-bat off the bench before the day is out.”

It doesn’t seem as though Renfroe minds which camp he falls into on a given day.

“Whether I’m starting or coming off the bench, I don’t care,” he said. “I just want to win and go to the World Series.”

Padres pitchers scuffle
Greinke got his revenge in the fourth, when he smashed a cutter from Eric Lauer over the center-field wall, putting the D-backs on top, 4-2. Two innings later, the veteran right-hander went deep again, this time off reliever Adam Warren.

“We know Greinke can hit,” Green said. “He’s one of the best-hitting pitchers in the game. We respect the bat. Just didn’t make good pitches to him.”

Greinke wasn’t the only hitter to tag Padres pitching on Tuesday night. Ketel Marte also homered against Lauer, who allowed four runs in five innings. Warren allowed three homers over two ugly frames.

Tatis’ glove dazzles again
In his first big league homestand, Fernando Tatis Jr. has already put all five of his tools on full display. On Tuesday night, his defense took center stage.

The 20-year-old top prospect made an acrobatic catch at shortstop, robbing Greinke of another hit. It came one day after he had launched his first career home run into the left-field seats.

In the top of the second inning, Greinke lifted a blooper toward left field. Tatis backpedaled, then adjusted on the fly as he opened his body. He went-full extension with his left arm for a sensational catch as he fell to the turf and barrel rolled. Lauer doffed his cap in appreciation.

After a 1-for-4 night, Tatis is hitting just .227 this season. But he’s made it clear that his impact extends well beyond the batters’ box.

Tidbits
• The Padres’ five runs were the most they’ve scored in a game this season. Said Green: “The first series, the guys were over-amped. They really wanted to come through for the fans. I think we’re starting to settle into normal at-bats right now. I think that’s going to translate into better quality.”

• The two teams combined for eight home runs, one shy of the Petco Park record, accomplished most recently on Sept. 20, 2017 -- also in a game between the Padres and D-backs.

• Greinke is the first visiting pitcher to go deep at Petco Park since Bartolo Colon’s famed 2016 home run off James Shields.