The Yankees and Orioles, each in the thick of the American League postseason chase, go head to head at Camden Yards with hopes of increasing their postseason chances as part of a slate of nine games streaming live on MLB.TV.
New York finds itself within striking distance of the first-place Red Sox, while Baltimore is not far behind, as the O's look to jostle their way up the AL Wild Card standings in an extremely tight race.
Right-hander Sonny Gray, the Yankees' prized acquisition at the non-waiver Trade Deadline, has excelled since moving to the Bronx. The former A's ace has limited opponents to a .203 batting average with a 3.16 ERA in pinstripes.
Gray will square off against right-hander Kevin Gausman, who has been a completely different pitcher in the second half than he was before the All-Star break. Gausman went 5-7 with a 5.85 ERA in 19 starts before the break, and he has a 5-2 record and a 3.12 ERA in 10 starts since.
First pitch is scheduled for 1:35 p.m. ET in a makeup from Wednesday's game, which was postponed due to inclement weather.
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Here's what to watch for throughout the day (all times ET):
Indians seek 15th straight win: CLE@CWS, 8:10 p.m.
The first-place Indians stand one victory away from franchise history. The Tribe can set a club record with 15 wins in a row if it beats the White Sox tonight to complete a four-game sweep in Chicago.
Cleveland, which leads the Twins by 11 games in the AL Central, has the right man for the job on the mound in ace Corey Kluber, who is once again in the mix for the AL Cy Young Award. Kluber leads the AL with a 2.56 ERA and a 0.90 WHIP to go along with 14 wins in 24 starts.
Left-hander Carlos Rodon will toe the rubber for the White Sox. He pitched one of his best games of the year the last time he faced the Indians, striking out nine and allowing one run on six hits in 6 2/3 innings in a no-decision on July 30.

Lester goes for Cubs: CHC@PIT, 7:05 p.m.
Jonathan Lester starts for the Cubs in the finale of a four-game series against the Pirates, who will counter with right-hander Jameson Taillon. The Cubs lead the National League Central and are looking to put more ground between themselves and the Cardinals and Brewers.
For Lester, it's his second start since coming off the disabled list at the end of August. The left-hander has a 5.32 ERA in his last 17 starts, though Lester and the Cubs believe he'll regain his form moving forward.
"We're all good," Lester said. "Moving in the right direction."
Taillon worked six scoreless innings in a no-decision against the Reds his last time out. He's 2-3 with a 6.75 ERA in 10 starts since the All-Star break.

Nats look to reduce magic number: PHI@WSH, 7:05 p.m.
The Nationals return to Nationals Park for a 10-game homestand with their magic number to clinch the NL East over the Marlins down to six games.
Tanner Roark starts for the Nats, who are coming off a three-game sweep in Miami. In the second half of the season, Roark has a 3.05 ERA in nine starts. Aaron Nola will take the mound for the Phillies in the opener of this four-game series. He is 1-0 with a 3.27 ERA in two starts against the Nats this season.

Big series at The K: MIN@KC, 8:15 p.m.
The Twins have a slim lead in the race for the second AL Wild Card, making this series in Kansas City all the more important. The Twins lead the Angels by a half-game, while the Royals are just 2 1/2 back.
Kyle Gibson starts for the Twins, who snapped a three-game losing skid on Wednesday. He has been sensational over his last three starts, going 3-0 with a 1.37 ERA.
The Royals will get their first look at right-hander Sam Gaviglio, who gets the ball in his debut for the club after being claimed off outright waivers from Seattle on Friday.
"I'm really excited," said Gaviglio, who was 3-5 with a 4.63 ERA in 12 games (11 starts) with the Mariners this season. "I'm looking forward to helping this team out."

Kershaw faces Rockies: COL@LAD, 10:10 p.m.
Dodgers ace Clayton Kershaw makes his first start in front of the home crowd since returning from the disabled list on Aug. 31 in San Diego. The Dodgers can clinch a playoff spot with a victory and losses by both the Cubs and Cardinals.
Jon Gray takes the mound for the Rockies, who are holding onto the second NL Wild Card spot. Gray has been solid since returning from a stress fracture in his foot June 30, allowing three runs or fewer in 10 of his last 12 starts.