Two of the premier teams in baseball go head-to-head for an intriguing Interleague matchup when the Nationals take on the Astros as part of a loaded 16-game slate Tuesday streaming live on MLB.TV.
The clubs, which both hold sturdy leads atop their respective divisions, have not met since 2014 when the Nationals swept the season series (two games in Washington, two in Houston). It will be the teams' third series overall since Houston moved to the American League in 2013.
The Nationals send right-hander Tanner Roark to the mound to face an Astros team that has not been as dominant as it had been earlier in the year, but is still quite dangerous. Roark picked up a win back in '14 versus Houston, giving up just one run in five innings of work in his only career outing against the Astros.
The Astros, who still hold the AL's best record despite their recent struggles, counter with right-hander Charlie Morton. The 33-year-old has excelled since the All-Star break, going 3-2 with a 3.03 ERA with 41 strikeouts in 38 2/3 innings.
First pitch is scheduled for 8:10 p.m. ET at Minute Maid Park.
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Here's what else to watch for throughout the day (all times ET):
ALDS rematch: BOS@CLE, 7:10 p.m.
The series between two of the AL's best teams continues tonight as Boston's Doug Fister and Cleveland's Carlos Carrasco square off at Progressive Field.

Fister, 33, has faced the Indians twice this season. The veteran is 1-1 with seven runs allowed in 12 innings versus the Tribe in 2017.
Since giving up five earned runs in consecutive starts to begin August, Carrasco has pulled off back-to-back victories while permitting just one run in 13 innings with 19 strikeouts.
Holland's royal return: COL@KC, 8:15 p.m.
A lethal force out of the bullpen in his Royals career, Greg Holland makes his return to Kansas City for the first time since signing a one-year deal with the Rockies this past offseason.
Holland, a two-time All-Star with the Royals, went 18-12 with a 2.42 ERA and 145 saves while pitching in parts of six seasons with the club. This season, Holland has been Colorado's go-to guy, racking up 35 saves to pair with a 3.22 ERA.

The 31-year-old will look to turn around a tough month of August in which he's gone 1-3 with a 12.79 ERA. Right-hander Jon Gray (5-2, 4.74) and Danny Duffy (7-8, 3.82) are the scheduled starters.
Wild, Wild West: TEX@LAA, 10:07 p.m.
Look for the ball to be flying at Angel Stadium in Anaheim. Not only do both the Rangers have one of the most potent lineups in baseball when it comes to hitting homers, but Angels starter Ricky Nolasco has allowed a whopping 31 long balls this season.
Tyson Ross toes the rubber for Texas as he tries to turn things around. He's 3-2 with a 7.02 ERA in nine starts in 2017 and has surrendered six homers in 42 1/3 frames.

The contest has potentially large implications in the AL Wild Card race, as both teams find themselves in the thick of the hunt for a playoff spot.