Guardians Roster & Staff
Transactions
| Date | Transaction |
| 05/22/25 | Cleveland Guardians activated CF Lane Thomas from the 10-day injured list. |
| 05/22/25 | Cleveland Guardians placed RF Will Brennan on the 10-day injured list. Left forearm inflammation. |
| 05/22/25 | Cleveland Guardians optioned LHP Doug Nikhazy to Columbus Clippers. |
| 05/21/25 | Cleveland Guardians recalled LHP Doug Nikhazy from Columbus Clippers. |
| 05/20/25 | Cleveland Guardians placed RF Will Brennan on the 10-day injured list. Left forearm inflammation. |
| 05/20/25 | Cleveland Guardians signed free agent SS Michael Turconi to a minor league contract. |
| 05/19/25 | Cleveland Guardians sent 1B David Fry on a rehab assignment to Akron RubberDucks. |
| 05/17/25 | Cleveland Guardians activated RHP Slade Cecconi from the 15-day injured list. |
| 05/17/25 | Cleveland Guardians optioned RHP Zak Kent to Columbus Clippers. |
| 05/13/25 | Cleveland Guardians sent CF Lane Thomas on a rehab assignment to Columbus Clippers. |
| 05/13/25 | Cleveland Guardians placed RHP Ben Lively on the 15-day injured list. Right forearm strain. |
| 05/13/25 | Cleveland Guardians recalled RHP Zak Kent from Columbus Clippers. |
| 05/12/25 | Cleveland Guardians sent 1B David Fry on a rehab assignment to ACL Guardians. |
| 05/12/25 | Cleveland Guardians activated RF Will Brennan. |
| 05/12/25 | Cleveland Guardians recalled RF Will Brennan from Columbus Clippers. |
| 05/12/25 | Cleveland Guardians optioned SS Brayan Rocchio to Columbus Clippers. |
| 05/10/25 | Cleveland Guardians signed free agent RHP Victor De Jesus to a minor league contract. |
| 05/08/25 | Cleveland Guardians signed free agent RHP Jesus Luna to a minor league contract. |
| 05/07/25 | Cleveland Guardians optioned RHP Zak Kent to Columbus Clippers. |
| 05/06/25 | Cleveland Guardians recalled RHP Zak Kent from Columbus Clippers. |
| 05/04/25 | Cleveland Guardians sent RHP Vince Velasquez outright to Columbus Clippers. |
| 05/02/25 | Cleveland Guardians designated RHP Vince Velasquez for assignment. |
| 05/02/25 | Cleveland Guardians selected the contract of RHP Matt Festa from Columbus Clippers. |