Guardians Roster & Staff
Transactions
| Date | Transaction |
| 07/31/16 | Cleveland Indians designated LF Joey Butler for assignment. |
| 07/31/16 | Cleveland Indians signed free agent RHP Lendy Castillo to a minor league contract. |
| 07/31/16 | New York Yankees traded LHP Andrew Miller to Cleveland Indians for RHP Ben Heller, CF Clint Frazier, RHP J.P. Feyereisen and LHP Justus Sheffield. |
| 07/31/16 | New York Yankees traded LHP Andrew Miller to Cleveland Indians for RHP Ben Heller, CF Clint Frazier, RHP J.P. Feyereisen and LHP Justus Sheffield. |
| 07/31/16 | New York Yankees traded LHP Andrew Miller to Cleveland Indians for RHP Ben Heller, CF Clint Frazier, RHP J.P. Feyereisen and LHP Justus Sheffield. |
| 07/31/16 | New York Yankees traded LHP Andrew Miller to Cleveland Indians for RHP Ben Heller, CF Clint Frazier, RHP J.P. Feyereisen and LHP Justus Sheffield. |
| 07/31/16 | New York Yankees traded LHP Andrew Miller to Cleveland Indians for RHP Ben Heller, CF Clint Frazier, RHP J.P. Feyereisen and LHP Justus Sheffield. |
| 07/29/16 | Cleveland Indians activated RHP Zach McAllister from the 15-day injured list. |
| 07/29/16 | Cleveland Indians placed RHP Jeff Manship on the 15-day disabled list retroactive to July 27, 2016. Right wrist tendonitis. |
| 07/25/16 | Cleveland Indians sent RHP Zach McAllister on a rehab assignment to Akron RubberDucks. |
| 07/24/16 | Cleveland Indians signed OF Jhon Torres. |
| 07/23/16 | Cleveland Indians signed free agent LHP Joe Thatcher to a minor league contract. |
| 07/22/16 | Joseph Colon roster status changed by Cleveland Indians. |
| 07/22/16 | Cleveland Indians recalled Cody Anderson from Columbus Clippers. |
| 07/21/16 | Cleveland Indians signed free agent SS Jonathan Lopez to a minor league contract. |
| 07/18/16 | Cleveland Indians recalled Kyle Crockett from Columbus Clippers. |
| 07/18/16 | Cleveland Indians placed C Yan Gomes on the 15-day disabled list. Separated right shoulder. |
| 07/18/16 | Cleveland Indians sent RHP Zach McAllister on a rehab assignment to Columbus Clippers. |
| 07/18/16 | Cleveland Indians activated C Roberto Perez from the 60-day injured list. |
| 07/18/16 | Cleveland Indians optioned RHP Cody Anderson to Columbus Clippers. |
| 07/17/16 | Cleveland Indians traded LHP Ross Detwiler to Oakland Athletics for cash. |
| 07/17/16 | Cleveland Indians placed RHP Tommy Hunter on the 15-day disabled list retroactive to July 10, 2016. Non-baseball related injury. |
| 07/17/16 | Cleveland Indians recalled Cody Anderson from Columbus Clippers. |
| 07/16/16 | Cleveland Indians signed free agent RHP Ignacio Feliz to a minor league contract. |
| 07/15/16 | Cleveland Indians sent OF Michael Brantley on a rehab assignment to Akron RubberDucks. |
| 07/15/16 | Cleveland Indians signed free agent RHP Luis Garcia to a minor league contract. |
| 07/14/16 | Cleveland Indians recalled Erik Gonzalez from Columbus Clippers. |
| 07/14/16 | Cleveland Indians sent C Roberto Perez on a rehab assignment to Columbus Clippers. |
| 07/13/16 | Cleveland Indians sent OF Michael Brantley on a rehab assignment to Lake County Captains. |
| 07/13/16 | Cleveland Indians sent C Roberto Perez on a rehab assignment to Lake County Captains. |
| 07/13/16 | Cleveland Indians optioned LHP TJ House to Columbus Clippers. |
| 07/12/16 | Cleveland Indians signed free agent SS Makesiondon Kelkboom to a minor league contract. |
| 07/11/16 | Cleveland Indians sent OF Michael Brantley on a rehab assignment to Mahoning Valley Scrappers. |
| 07/10/16 | Cleveland Indians released RHP Joba Chamberlain. |
| 07/09/16 | Cleveland Indians optioned LHP Tyler Olson to Columbus Clippers. |
| 07/09/16 | Cleveland Indians claimed LHP Tyler Olson off waivers from Kansas City Royals. |
| 07/08/16 | Cleveland Indians traded 2B Michael Martinez to Boston Red Sox. |
| 07/08/16 | Cleveland Indians sent LHP Tom Gorzelanny outright to Columbus Clippers. |
| 07/07/16 | Cleveland Indians recalled Austin Adams from Columbus Clippers. |
| 07/07/16 | Cleveland Indians recalled RHP Joseph Colon from Columbus Clippers. |
| 07/07/16 | Cleveland Indians optioned RHP Mike Clevinger to Columbus Clippers. |
| 07/07/16 | Cleveland Indians placed RHP Zach McAllister on the 15-day disabled list. Right hip discomfort. |
| 07/06/16 | Cleveland Indians signed LHP Raymond Burgos. |
| 07/04/16 | Cleveland Indians recalled Mike Clevinger from Columbus Clippers. |
| 07/04/16 | Cleveland Indians designated RHP Joba Chamberlain for assignment. |
| 07/04/16 | Cleveland Indians designated LHP Tom Gorzelanny for assignment. |
| 07/04/16 | Cleveland Indians recalled TJ House from Columbus Clippers. |
| 07/04/16 | Cleveland Indians signed CF Andrew Calica. |
| 07/03/16 | Cleveland Indians optioned LHP Shawn Morimando to Columbus Clippers. |
| 07/03/16 | Cleveland Indians transferred LF Michael Brantley from the 15-day disabled list to the 60-day disabled list. November 2015 right shoulder surgery |
| 07/03/16 | Cleveland Indians activated LF Abraham Almonte from the restricted list. |
| 07/02/16 | Cleveland Indians recalled Shawn Morimando from Akron RubberDucks. |
| 07/02/16 | Cleveland Indians signed free agent SS Marcos Gonzalez to a minor league contract. |
| 07/02/16 | Cleveland Indians signed free agent 3B Jeikol Contreras to a minor league contract. |
| 07/02/16 | Cleveland Indians signed free agent RHP Juan Paredes to a minor league contract. |
| 07/02/16 | Cleveland Indians selected the contract of RHP Joseph Colon from Columbus Clippers. |
| 07/02/16 | Cleveland Indians designated 2B Michael Martinez for assignment. |
| 07/02/16 | Cleveland Indians signed free agent 3B Nehemias Celesten to a minor league contract. |
| 07/02/16 | Cleveland Indians signed free agent IF Jesus Maestre to a minor league contract. |
| 07/02/16 | Cleveland Indians signed free agent SS Gaspar Palacio to a minor league contract. |
| 07/02/16 | Cleveland Indians optioned Joseph Colon to Columbus Clippers. |
| 07/02/16 | Cleveland Indians signed free agent RHP Eric Perez to a minor league contract. |
| 07/02/16 | Cleveland Indians signed free agent RHP Carlos Vargas to a minor league contract. |
| 07/01/16 | Cleveland Indians sent C Roberto Perez on a rehab assignment to AZL Indians. |
| 07/01/16 | Cleveland Indians signed 3B Nolan Jones. |