The Rule 5 Draft allows clubs without a full 40-man roster to select non-40-man roster players from other clubs. Players signed at 18 years old or younger must be added to their club's 40-man roster within five seasons, and players who signed at 19 or older need to be protected within four seasons.
Houston outrighted two players -- left-hander Kent Emanuel and infielder Freudis Nova -- to make room for the others on the 40-man roster. Emanuel was claimed by the Phillies, while Nova went unclaimed and was assigned to Triple-A Sugar Land. The Astros' 40-man roster is full.
Bermudez was Houston's 2021 Minor League Pitcher of the Year after posting a 3.24 ERA in 25 games between Triple-A Sugar Land and Double-A Corpus Christi. A 23rd-round pick in 2018, Bermudez struck out 146 hitters in 111 innings.
Peña is the Astros' No. 4-ranked prospect, per MLB Pipeline. He missed the first three months of the Minor League season after undergoing left wrist surgery, but he played 30 games with Triple-A Sugar Land, slashing .287/.346/.598.
Dubin, the club's No. 11 prospect, went 4-3 with one save and a 3.44 ERA with the Skeeters this season. A 13th-round pick in the 2018 MLB Draft, Dubin struck out 69 batters over 49 2/3 innings.
Perez, the No.9-ranked prospect, spent time at three Minor League levels this season. He finished the year at Double-A Corpus Christi, where he compiled 19 doubles, eight home runs and 27 RBIs in 69 games for the Hooks. Overall, he had a .291/.354/.495 slash line between Corpus Christi, High-A Asheville and Low-A Fayetteville.