CHICAGO – The White Sox 8-2 loss to the Twins on Wednesday night at Guaranteed Rate Field was not one of the cleanest 2019 efforts from Rick Renteria’s crew.

And against a team built like the American League Central leaders, extra outs usually result in extra runs.

“You have to play good baseball. You have to play clean baseball,” said Renteria after his team slipped to 5-10 on the season against Minnesota. “If you are going against a club that has the ability to string together a lot of different things, in terms of generating runs, you can’t let them in. You’ve got to do what we’ve been doing a lot this year, minimizing the damage from the other side, actually playing decent baseball.”

• Box score

Here’s a look at a few key White Sox developments from Wednesday’s setback, dropping the White Sox to 3-3 on the homestand.

Tough night for Tim

Shortstop Tim Anderson deservedly has been praised for his development at the position and the range he consistently shows in the field. But Wednesday’s game was not one of those moments supporting the praise.

Eddie Rosario opened the second with what was ruled a single to center. The high popup, which had an xBA of .190 per Statcast, was called for by shortstop Anderson, but it fell just outside of his glove on a catchable play. That extra out allowed Jonathan Schoop to connect for a two-out, three-run home to left. Schoop homered again in the eighth off Chicago reliever Jace Fry, as the Twins scored three times to open up a rather tight game.

“Just missed it,” Anderson said of the popup.

“The fly ball, I thought he should have had,” Renteria said. “At the end, he was commanding it clearly. Probably heard some footsteps, pulled up a little bit, but he should have had that ball.”

Later, in the third inning, Miguel Sano ripped a grounder with a 110.6-mph exit velocity toward Anderson for what looked to be an inning-ending double play after Sano tried to call time before stepping back in the box. But the ball went through Anderson’s legs for his Major League-leading 24th error. The Twins scored two in the frame, giving starting pitcher Jake Odorizzi plenty of support.

Bench coach Joe McEwing talked with Anderson about the miscue, and Renteria believes Anderson was caught flat-footed after assuming time had been called.

“I'm going to go to bed tonight and wake up tomorrow. I don't think about it,” Anderson said. “It happens. Tomorrow's a new day.”

At the plate, Anderson went 2-for-4 with a double, giving him an American League-best 42 hits over 26 games in August. His average sits at a robust .329.

Detwiler deserved better

All five of the runs allowed by White Sox starter Ross Detwiler were earned, raising his ERA to 5.96. But the veteran southpaw, who struck out five in four innings, deserved a better fate.

Detwiler put the blame upon himself for the final numbers.

“I was good here and there, not the whole time. There were some mistakes,” Detwiler said. “I paid for the mistakes. I kind of lost focus, lost the strike zone a little bit in the second. Ultimately, that's what put us in a hole.”

Exit on a high note

There were a few individual highlights for the White Sox.

Leury Garcia took a home run away from C.J. Cron with a leaping catch at the well in the second inning, and Yoan Moncada made three slick backhand pickups at third as well as ending a season-high hitless streak at 12 at-bats with a single in the fourth.

Jose Abreu doubled home a run in the first, giving him 101 RBIs and 30 doubles on the year, making him the first player in franchise history to have six straight years of at least 30 doubles. Abreu previously was tied at five with Magglio Ordonez (1999-2003).

Ultimately, this loss became an infrequent exception from the White Sox amid the better brand of baseball they have played overall in ’19.

“This is not indicative of the way we’ve been playing all year. The guys aren’t going to be perfect,” Renteria said. “At the end of the day, you have to stay focused and play good baseball and not give anything away to clubs like this.”