Betts injured his foot sliding into Baltimore catcher Chance Sisco in the first inning, limping off the field and leaving the dugout to receive treatment. Betts initially stayed in the game, even coming to the plate again in the second inning, but couldn't finish it out.
With Betts out, the Red Sox inserted Blake Swihart into the game in left field and moved Andrew Benintendi to center field with Bradley shifting to right field. It was the first time Swihart had played left at Fenway Park since he suffered a season-ending ankle injury crashing into the wall along the left-field foul line in 2016.
Brian MacPherson is a contributor to MLB.com based in Boston.