MINNEAPOLIS -- The Red Sox lost emerging star Rafael Devers in the fifth inning of Wednesday's 9-4 win over the Twins due to a right hamstring strain which isn't believed to be serious.

The Sox are off on Thursday, and manager Alex Cora expects to keep Devers out of the lineup on Friday as a precaution. He could be back soon thereafter.

Devers appeared to wince after legging out an infield single as the second batter of the inning. After Devers advanced to third on an RBI double by Xander Bogaerts, he was replaced by pinch-runner Eduardo Núñez.

"He's OK," said Cora. "Day to day. Most likely we'll stay away from him Friday. He'll get treatment tomorrow. He was OK at first, then when he got to third, I was like, 'No, let's not take a chance here.'"

Brock Holt, Michael Chavis and Nunez can all fill in at third until Devers returns.

"I just felt that it was a little bit tight," said Devers through an interpreter. "It's not as bad as what I dealt with last year and hopefully I can go out there and play, but it's up to the coaches to see if they let me play on Friday."

Devers is off to a strong start that could propel him to be an All-Star for the first time. The left-handed hitter is slashing .307/.360/.503 with 12 homers and 47 RBIs.