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Thursday
7:05 p.m. ET: Charlotte Knights (CWS) vs. Jacksonville Jumbo Shrimp (MIA)
The same week premier left-hander Noah Schultz heads to The Show, the other top White Sox pitching prospect, Hagen Smith (CWS No. 4/MLB No. 65), and MLB’s top southpaw prospect Thomas White (MIA No. 1/MLB No. 14) are set to go toe to toe. The outing will be White’s first at Triple-A this season after making two Single-A starts while rehabbing from a Grade 1 right oblique strain. The 21-year-old attacks hitters with a three-pitch mix led by his 70-grade slider. Smith has three starts under his belt for Charlotte this season, and he has tallied 14 strikeouts and held opponents to a .212 average through nine innings.
9:35 p.m. ET: Fresno Grizzlies (COL) vs. Ontario Tower Buzzers (LAD)
Matt Holliday was named to seven All-Star teams over his 15-year big league career. Son Jackson tore up the Minor Leagues and debuted with Baltimore as a 20-year-old in 2024. Now it’s his other son’s turn to make his name for himself. Ethan Holliday (COL No. 1/MLB No. 20), the No. 4 pick in last year’s Draft, has been described as a closer physical representation of his father with massive raw power in his 6-foot-2, 210-pound frame -- a rarity for a shortstop. He’ll look to put that to use as the Rockies’ Single-A affiliate matches up against Emil Morales (LAD No. 5/MLB No. 84) and Ontario. Morales, an international signee in 2024, has mashed at every level since turning pro. Last season, he paced the Rookie-level Arizona Complex League in hits (70), extra-base hits (25) and total bases (116) before moving to Single-A and posting a .968 OPS.
Friday
2 p.m. ET: Bradenton Marauders (PIT) vs. Tampa Tarpons (NYY)
When Paul Skenes was in the Minors, every one of his 12 appearances was a spectacle. Two outings into his professional career, Seth Hernandez (PIT No. 2/MLB No. 25) is starting to have the same effect for Single-A Bradenton. The 2025 first-rounder has racked up 15 strikeouts over seven innings and held opponents -- who are whiffing 66 percent of the time -- to a .130 average-against. What will his next start bring? That’s in the hands of Tampa and Cuban outfielder Brando Mayea, the ninth-ranked international signee in the 2023 class.
6:05 p.m. ET: Dayton Dragons (CIN) vs. Great Lakes Loons (LAD)
It’s not often that a catcher drives a team’s offense -- aside from the Mariners' Cal Raleigh last season -- but Alfredo Duno (CIN No. 1/MLB No. 34) does just that. The 20-year-old backstop led the Florida State League with 18 homers in 2025 and entered this week with knocks in six of his eight games this year. He’ll lead the Reds' High-A prospects against Great Lakes and a pair of Dodgers Top 100 outfielders -- Eduardo Quintero (LAD No. 3/MLB No. 26) and Mike Sirota (LAD No. 4/MLB No. 55). Quintero has true five-tool potential at just 20 years old. Last season, he swiped 47 bases and hit 19 homers. Sirota may be best known for his speed, but has also shined with the bat, posting a 1.068 OPS in his debut season in 2025.
Saturday
2:05 p.m. ET: Gwinnett Stripers (ATL) vs. Memphis Redbirds (STL)
There may not be a pitcher in the Minors who has been as dominant as JR Ritchie (ATL No. 2/MLB No. 82) to start the season. The 22-year-old right-hander has a 1.27 ERA through four Triple-A starts (two of which were scoreless) and a 1.03 WHIP. He keeps opponents on their toes with a six-pitch mix. In Ritchie's second outing last week against the same team, the opponent couldn't manage a run off him. His next task will be to shut down a daunting Memphis lineup headlined Joshua Báez (STL No. 4/MLB No. 79) and Leo Bernal (STL No. 6/MLB No. 89). Báez, who broke out with 20 big flies in 2025, closed last week with homers in two of his final three games.
6:05 p.m. ET: Binghamton Rumble Ponies (NYM) vs. Akron RubberDucks (CLE)
Ralphy Velazquez (CLE No. 4/MLB No. 81) became a popular pick to break out in 2026 after closing last year's campaign with a .330/.405/.589 slash line and five homers over 28 Double-A contests. His early-season performance has backed that up. Velazquez entered the week with two homers and knocks in all but one game. His Akron running mate, Angel Genao (CLE No. 3/MLB No. 60) reached base in his first eight games. Headlining Binghamton is A.J. Ewing (NYM No. 3/MLB No. 88). The 21-year-old surged up prospect rankings last season due to his knack for getting on base and his 70-grade run tool.
Sunday
6:35 p.m. ET: Kannapolis Cannon Ballers (CWS) vs. Myrtle Beach Pelicans (CHC)
Gold Glove-caliber defense plays at any level, and while Billy Carlson (CWS No. 5/MLB No. 66) is only 19 years old, he already has the makings of an elite defensive shortstop. The 2025 first-rounder features a 70-grade fielding tool -- the highest mark among Top 100 prospects -- and a 70-grade arm to match. He'll be locking down the six as Single-A Kannapolis takes 2025 sixth-rounder Josiah Hartshorn (CHC No. 7) and Myrtle Beach. A switch-hitting outfielder, Hartshorn was crowned the co-champion of the All-Star High School Home Run Derby at Globe Life Field in 2024 after mashing 23 homers across two rounds.