TORONTO -- The Yankees crammed all their offense into one inning on Friday, and for a little while, it seemed like that would be enough. But the Blue Jays capitalized on a run-scoring balk to tie the game in the seventh and then Bo Bichette ended it with a walk-off home run in the 12th to hand the Yankees a 6-5 loss at the Rogers Centre.

Tyler Lyons, making just his fifth appearance since signing with the Yankees a month ago, left a slider middle-in for Bichette, who skied it to left field. Clint Frazier watched helplessly from the warning track as the ball carried over the wall.

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Bichette's homer was the only hit for either side in extra innings, which symbolized the ineffectiveness of New York's offense most of the evening.

"They matched it up a little in some different ways," Yankees manager Aaron Boone said of the Blue Jays, who deployed nine pitchers in the game. "Just couldn't get it going enough offensively outside that inning."

By "that inning," Boone means the fifth, in which the Yankees scored all five of their runs on five hits and a walk.

Brett Gardner led off the inning with a hustle double on a ball that bounced off a sliding Teoscar Hernandez in center field. Then Frazier blooped a double into shallow right field (only 56.4 mph exit velocity) and advanced to third on an errant throw. Austin Romine and DJ LeMahieu followed with a pair of two-strike singles. Gio Urshela later singled as well, and Didi Gregorius walked.

It was a turning point that chased Toronto starter Anthony Kay (making just his second MLB start) and put New York on top, 5-3. But the game would turn again.

In the seventh, with a one-run lead and runners on the corners, New York reliever Adam Ottavino took a misstep as he attempted a pick-off move and was called for a balk. That allowed Richard Urena to advance home from third and tie the game.

"I have to be sharper," said Ottavino, who has allowed a run in three-straight outings for the first time since last September. "I'm just not as sharp as I need to be right now."

New York's offense wasn't sharp enough either, providing no spark as the game wore on through extras.

As for Yankees starter Masahiro Tanaka, nothing was easy after a clean first inning.

After allowing a pair of runs in the fourth, he sat for 35 minutes while the Yankees went to work with its five-run eruption. When Tanaka came back out, it took only two minutes for him to get into trouble: allowing a lead-off double to Bichette, followed by an RBI single for Cavan Biggio to cut the Yankees' lead to 5-4.

That would be the end of the damage against Tanaka, though, who yielded eight hits and four earned runs in five innings. It wasn't his usual dominance over the Blue Jays (he'd been 4-1 with a 1.97 ERA in five previous starts against them), and he knew it.

"Just couldn't really hold them down when I needed to," Tanaka said.

"They dinged him enough, obviously," Boone said of Tanaka. "Made him work there in the fourth and fifth, but [he] left us with a chance to win the game."

The Yankees, of course, didn't win the game. That means their magic number to lock up the American League East remains at five. Chipping away at that number isn't easy right now, as the Yankees are in the midst of 11 road games in a 10-day span.

The past two days have been particularly trying -- a doubleheader on a travel day Thursday in Detroit (in which three players left with injuries), followed by a 12-inning game that stretched into the final hour of Friday night.

"You know you're gonna go through points in the schedule like that and you try to navigate it the best you can," Boone said. "And we need to come out ready to go tomorrow and try and grab one back."