He has been on the disabled list since the end of May with right triceps tendinitis. After feeling pain during a bullpen session on Thursday, Darvish will not make his return Saturday against the Twins as had been expected. Tyler Chatwood will start for the Cubs instead.
Darvish's relationship with Meister dates back to the right-hander's time with Texas, where Darvish played from 2012 until he was traded to the Dodgers just prior to the non-waiver Trade Deadline last season.
"It was easy" for Maddon to tell Darvish wasn't right on Thursday because it "wasn't a normal throwing stroke."
The setback comes after Darvish threw a successful simulated game last week and a rehab start on Monday for Class A South Bend. Maddon said he assumes that whenever Darvish does come back, the righty will need another rehab start before returning to the Majors, though that hadn't been determined.
"I would bet another rehab," Maddon said. "That's what normally would occur."
Darvish is 1-3 with a 4.95 ERA in eight starts this season, his first with the Cubs after signing a six-year deal in February.
Bryant resumes baseball activities Third baseman Kris Bryant was scheduled to hit in the cages Friday, starting with tee work and progressing from there based on how he felt, and also would take grounders, according to the Cubs.
"He's feeling a lot better," Maddon said.
Bryant was placed on the 10-day disabled list with left shoulder inflammation Tuesday, retroactive to Saturday. He is eligible to come off the DL on Tuesday, and the club says that as long as Bryant continues to feel well, he won't need to do much before returning to the lineup.
Relievers nearing return Right-handed relievers Carl Edwards Jr. and Eddie Butler are getting closer to coming off the disabled list. Edwards will make a Minor League rehab outing with Triple-A Iowa on Friday. Butler was traveling to Iowa on Friday and will make a rehab appearance there Saturday.
Baby Baez Javier Baez announced Friday on Twitter that he and fiancee Irmarie Marquez had welcomed a newborn son.