Mets Roster & Staff
Transactions
| Date | Transaction |
| 05/31/22 | New York Mets signed free agent RHP Wilson Lopez to a minor league contract. |
| 05/31/22 | New York Mets optioned 1B Dominic Smith to Syracuse Mets. |
| 05/31/22 | New York Mets recalled RHP Adonis Medina from Syracuse Mets. |
| 05/28/22 | New York Mets activated RHP Yoan Lopez. |
| 05/28/22 | New York Mets recalled CF Nick Plummer and from Syracuse Mets. |
| 05/28/22 | Cincinnati Reds traded SS JT Riddle to New York Mets. |
| 05/28/22 | New York Mets optioned RHP Yoan Lopez to Syracuse Mets. |
| 05/27/22 | New York Mets placed CF Travis Jankowski on the 10-day injured list retroactive to May 26, 2022. Left 4th metacarpal fracture. |
| 05/27/22 | RHP Yoan Lopez roster status changed by New York Mets. |
| 05/27/22 | New York Mets recalled RHP Yoan Lopez from Syracuse Mets. |
| 05/27/22 | New York Mets recalled RHP Stephen Nogosek from Syracuse Mets. |
| 05/26/22 | New York Mets optioned LHP Thomas Szapucki to Syracuse Mets. |
| 05/25/22 | New York Mets signed free agent OF Karell Paz to a minor league contract. |
| 05/25/22 | Cleveland Guardians traded RF Daniel Johnson to New York Mets. |
| 05/25/22 | New York Mets optioned RHP Stephen Nogosek to Syracuse Mets. |
| 05/25/22 | New York Mets recalled LHP Thomas Szapucki from Syracuse Mets. |
| 05/24/22 | New York Mets signed free agent RHP Wander Rosario to a minor league contract. |
| 05/23/22 | New York Mets optioned RHP Jake Reed to Syracuse Mets. |
| 05/23/22 | New York Mets recalled LHP David Peterson from Syracuse Mets. |
| 05/22/22 | New York Mets optioned RHP Adonis Medina to Syracuse Mets. |
| 05/21/22 | New York Mets placed RHP Max Scherzer on the 15-day injured list retroactive to May 19, 2022. Left oblique strain. |
| 05/21/22 | New York Mets activated LF Starling Marte from the bereavement list. |
| 05/21/22 | New York Mets recalled RHP Jake Reed from Syracuse Mets. |
| 05/21/22 | New York Mets optioned 2B Gosuke Katoh to Syracuse Mets. |
| 05/21/22 | New York Mets recalled RHP Adonis Medina from Syracuse Mets. |
| 05/19/22 | New York Mets signed free agent RHP Trevor Cahill to a minor league contract. |
| 05/18/22 | New York Mets optioned RHP Adonis Medina to Syracuse Mets. |
| 05/17/22 | New York Mets recalled RHP Adonis Medina from Syracuse Mets. |
| 05/17/22 | New York Mets recalled 2B Gosuke Katoh from Syracuse Mets. |
| 05/17/22 | New York Mets optioned RHP Jake Reed to Syracuse Mets. |
| 05/17/22 | New York Mets recalled RHP Stephen Nogosek from Syracuse Mets. |
| 05/16/22 | New York Mets placed LF Starling Marte on the bereavement list. |
| 05/15/22 | New York Mets selected the contract of RHP Colin Holderman from Syracuse Mets. |
| 05/13/22 | New York Mets placed C James McCann on the 10-day injured list retroactive to May 11, 2022. Fracture of left hamate. |
| 05/13/22 | New York Mets recalled C Patrick Mazeika from Syracuse Mets. |
| 05/12/22 | New York Mets placed RHP Tylor Megill on the 15-day injured list. Right biceps inflammation. |
| 05/12/22 | New York Mets optioned LHP Locke St. John to Syracuse Mets. |
| 05/12/22 | New York Mets optioned RHP Stephen Nogosek to Syracuse Mets. |
| 05/12/22 | New York Mets recalled RHP Jake Reed from Syracuse Mets. |
| 05/10/22 | New York Mets transferred RHP Jacob deGrom from the 10-day injured list to the 60-day injured list. |
| 05/10/22 | New York Mets claimed LHP Locke St. John off waivers from Chicago Cubs. |
| 05/09/22 | New York Mets optioned RHP Adonis Medina to Syracuse Mets. |
| 05/08/22 | New York Mets released 2B Robinson Cano. |
| 05/08/22 | New York Mets recalled RHP Adonis Medina from Syracuse Mets. |
| 05/08/22 | New York Mets selected the contract of RHP Stephen Nogosek from Syracuse Mets. |
| 05/07/22 | New York Mets optioned 2B Gosuke Katoh to Syracuse Mets. |
| 05/07/22 | New York Mets claimed 2B Gosuke Katoh off waivers from Toronto Blue Jays. |
| 05/07/22 | New York Mets optioned RHP Adonis Medina to Syracuse Mets. |
| 05/04/22 | New York Mets optioned LHP David Peterson to Syracuse Mets. |
| 05/03/22 | New York Mets placed RHP Trevor May on the 15-day injured list. Right triceps inflammation. |
| 05/03/22 | New York Mets transferred RHP Trevor May from the 15-day injured list to the 60-day injured list. |
| 05/03/22 | New York Mets recalled RHP Adonis Medina from Syracuse Mets. |
| 05/03/22 | New York Mets recalled LHP David Peterson from Syracuse Mets. |
| 05/02/22 | New York Mets designated 2B Robinson Cano for assignment. |
| 05/02/22 | New York Mets optioned RHP Yoan Lopez to Syracuse Mets. |
| 05/01/22 | New York Mets placed RHP Sean Reid-Foley on the 60-day injured list. Partially torn right UCL. |
| 05/01/22 | New York Mets placed RHP Sean Reid-Foley on the 10-day injured list. Partially torn right UCL. |
| 05/01/22 | New York Mets recalled RHP Yoan Lopez from Syracuse Mets. |