Guardians Roster & Staff
Transactions
| Date | Transaction |
| 05/31/12 | Cleveland Indians signed free agent IF Juan Carlos Moncion to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent Francisco Miguel. |
| 05/31/12 | Cleveland Indians signed free agent OF Omar Sanchez to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent RHP Anthony Vizcaya to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent IF Ivan Castillo to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent OF Wilkin Acosta to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent OF Andri Santana to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent RHP Luis Aquino to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent RHP Jesus Beras to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent LHP Luis Gomez to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent LHP Edgar Pineda to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent RHP Johan Puello to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent Anderson Placido. |
| 05/31/12 | Cleveland Indians signed free agent RHP Alejandro Rivas to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent RHP Ramon Rodriguez to a minor league contract. |
| 05/31/12 | Cleveland Indians signed free agent RHP Junior Vincent to a minor league contract. |
| 05/30/12 | Cleveland Indians placed DH Travis Hafner on the 15-day disabled list retroactive to May 24, 2012. Sore right knee. |
| 05/30/12 | Cleveland Indians recalled Scott Barnes from Columbus Clippers. |
| 05/28/12 | Cleveland Indians placed 3B Jack Hannahan on the 15-day disabled list retroactive to May 27, 2012. Strained left calf. |
| 05/28/12 | Cleveland Indians activated RHP Josh Tomlin from the 15-day disabled list. |
| 05/28/12 | Cleveland Indians recalled 3B Lonnie Chisenhall from Columbus Clippers. |
| 05/28/12 | Cleveland Indians designated Jairo Asencio for assignment. |
| 05/26/12 | Cleveland Indians transferred LHP Rafael Perez from the 15-day disabled list to the 60-day disabled list. |
| 05/26/12 | Cleveland Indians placed C Carlos Santana on the 7-day disabled list. Concussion |
| 05/26/12 | Cleveland Indians selected the contract of Luke Carlin from Columbus Clippers. |
| 05/25/12 | Cleveland Indians recalled Juan Diaz from Akron Aeros. |
| 05/25/12 | Cleveland Indians optioned Zach McAllister to Columbus Clippers. |
| 05/18/12 | Cleveland Indians sent Nick Weglarz outright to Akron Aeros. |
| 05/16/12 | Cleveland Indians sent RHP Dan Wheeler outright to Columbus Clippers. |
| 05/14/12 | Cleveland Indians designated Dan Wheeler for assignment. |
| 05/14/12 | Cleveland Indians selected the contract of RHP Jeremy Accardo from Columbus Clippers. |
| 05/12/12 | Cleveland Indians recalled Zach McAllister from Columbus Clippers. |
| 05/12/12 | Cleveland Indians designated Nick Weglarz for assignment. |
| 05/12/12 | Cleveland Indians placed RHP Josh Tomlin on the 15-day disabled list retroactive to May 8, 2012. Sore right wrist. |
| 05/12/12 | Cleveland Indians optioned SS Jason Donald to Columbus Clippers. |
| 05/12/12 | Cleveland Indians selected the contract of 2B Jose Lopez from Columbus Clippers. |
| 05/08/12 | Cleveland Indians optioned Zach McAllister to Columbus Clippers. |
| 05/07/12 | Cleveland Indians recalled Zach McAllister from Columbus Clippers. |
| 05/04/12 | Cleveland Indians traded RF Ryan Spilborghs to Texas Rangers for cash. |
| 05/04/12 | Cleveland Indians traded RF Ryan Spilborghs to Texas Rangers for cash. |
| 05/03/12 | Cleveland Indians sent Jose Lopez outright to Columbus Clippers. |
| 05/01/12 | Cleveland Indians selected the contract of Johnny Damon from Mahoning Valley Scrappers. |
| 05/01/12 | Cleveland Indians designated Jose Lopez for assignment. |