Guardians Roster & Staff
Transactions
| Date | Transaction |
| 10/20/25 | Cleveland Guardians signed free agent RHP Antonio Gonzalez to a minor league contract. |
| 10/08/25 | RHP Luke House assigned to Cleveland Guardians. |
| 10/07/25 | Cleveland Guardians signed free agent RHP Jhonaiker Castillo to a minor league contract. |
| 10/03/25 | Cleveland Guardians activated LHP Logan Allen. |
| 10/03/25 | Cleveland Guardians activated CF Lane Thomas. |
| 10/03/25 | Cleveland Guardians activated RHP Nic Enright. |
| 10/03/25 | Cleveland Guardians activated LHP Doug Nikhazy. |
| 10/03/25 | Cleveland Guardians activated SS Juan Brito. |
| 10/03/25 | Cleveland Guardians activated RHP Zak Kent. |
| 10/03/25 | Cleveland Guardians activated RHP Daniel Espino. |
| 10/03/25 | Cleveland Guardians activated LHP Matt Krook. |
| 10/03/25 | Cleveland Guardians activated RF Nolan Jones. |
| 10/03/25 | Cleveland Guardians activated 1B David Fry. |
| 10/03/25 | Cleveland Guardians activated RHP Franco Aleman. |
| 10/03/25 | Cleveland Guardians activated C Dom Nuñez. |
| 10/03/25 | Cleveland Guardians activated LHP Parker Messick. |
| 10/03/25 | Cleveland Guardians activated 3B Will Wilson. |