Guardians Roster & Staff
Transactions
| Date | Transaction |
| 11/21/25 | RF Will Brennan elected free agency. |
| 11/21/25 | LHP Sam Hentges elected free agency. |
| 11/21/25 | RHP Nic Enright elected free agency. |
| 11/18/25 | Cleveland Guardians designated RHP Nic Enright for assignment. |
| 11/18/25 | Cleveland Guardians activated 3B Angel Genao. |
| 11/18/25 | Cleveland Guardians activated LF Kahlil Watson. |
| 11/18/25 | Cleveland Guardians activated RHP Yorman Gómez. |
| 11/18/25 | Cleveland Guardians activated RHP Austin Peterson. |
| 11/18/25 | Cleveland Guardians selected the contract of RHP Austin Peterson from Columbus Clippers. |
| 11/18/25 | Cleveland Guardians selected the contract of LF Kahlil Watson from Columbus Clippers. |
| 11/18/25 | Cleveland Guardians selected the contract of RHP Yorman Gómez from Akron RubberDucks. |
| 11/18/25 | Cleveland Guardians selected the contract of 3B Angel Genao from Akron RubberDucks. |
| 11/07/25 | Cleveland Guardians signed free agent RHP Carlos Hernández to a minor league contract. |
| 11/07/25 | RHP Carlos Hernández roster status changed by Cleveland Guardians. |
| 11/06/25 | Cleveland Guardians activated LHP Sam Hentges from the 60-day injured list. |
| 11/06/25 | Cleveland Guardians activated RHP Andrew Walters from the 60-day injured list. |
| 11/06/25 | LHP John Means elected free agency. |
| 11/06/25 | Cleveland Guardians activated RF Will Brennan from the 60-day injured list. |
| 11/06/25 | Cleveland Guardians sent LHP Matt Krook outright to Columbus Clippers. |
| 11/06/25 | Cleveland Guardians sent LHP Kolby Allard outright to Columbus Clippers. |
| 11/06/25 | Cleveland Guardians sent RHP Ben Lively outright to Columbus Clippers. |
| 11/06/25 | Cleveland Guardians sent 3B Will Wilson outright to Columbus Clippers. |
| 11/06/25 | Cleveland Guardians sent C Dom Nuñez outright to Columbus Clippers. |
| 11/02/25 | RHP Jakob Junis elected free agency. |
| 11/02/25 | CF Lane Thomas elected free agency. |