In the third inning, Prado pulled up after tapping a comebacker to right-hander Miles Mikolas with two outs. After taking a few steps out of the box, he began favoring his right leg.
“I'm sure Martin is extremely disappointed,” Marlins manager Don Mattingly said. “I haven't had a chance to talk with him yet, but I'm sure he's extremely disappointed. The guy loves being on the field.”
The Marlins are off on Thursday, and an injury list stint for Prado is expected before Friday’s series with the Pirates begins at Marlins Park.
“It felt like we were playing him right, where we were not killing him,” Mattingly said. “He had some days off. Keeping him three, four days a week.”
Prado has appeared in 51 games this season, and he is hitting .239 after going 1-for-2 with a single and run scored on Wednesday. In 155 at-bats, the veteran has seven doubles, one home run and 12 RBIs.
He opened the season splitting time at first base with Neil Walker, who currently is on the injured list with a right quad strain.
After walking slowly back to the dugout after the third inning, Prado was replaced by Austin Dean. Prado, who has played mostly first base this season, had gotten the nod at third base on Wednesday. The Marlins moved Brian Anderson from right field to third base to fill in for Prado. Dean went to left field, and Curtis Granderson switched from left to right field.
Prado, 35, has dealt with numerous injuries over the past two seasons, going on the injured list seven separate times. In that span, he’s been sidelined with right hamstring strains, left quad strains and a left abdominal strain.
In 2017, he underwent right knee surgery. He played just 37 games that season, and 54 total in 2018.