DraftKings picks: Votto, Cueto, Syndergaard

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The players listed below could provide difference-making stats for DraftKings participants on Tuesday.

Joey Votto (Reds): The first baseman could drive in multiple runs when he heads to hitter-friendly Citizens Bank Park to face Phillies righty Sean O'Sullivan (career 5.77 ERA). During his big league tenure, Votto has excelled against right-handers to the tune of a .974 OPS (.887 vs. lefties).

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Jay Bruce (Reds): Hitting .222 this season, Bruce could have a reduced cost in DraftKings contests when he brings his lifetime .811 OPS against right-handers (.732 vs. lefties) into a matchup with O'Sullivan (career 1.54 WHIP) at a homer-happy road venue.

Anthony Gose (Tigers): The outfielder -- who owns a lifetime .707 OPS against right-handers (.504 vs. lefties) and is hitting .314 with eight steals this season -- could reach base often when he faces A's righty Kendall Graveman (5.79 ERA, 1.68 WHIP in 2015). Once on base, Gose could successfully steal against Stephen Vogt, who has allowed more stolen bases (21) than all but four catchers in the Majors.

Pablo Sandoval (Red Sox): The third baseman could display some power when he brings his career .850 OPS against right-handers (.685 vs. lefties) into a home matchup with Twins righty Mike Pelfrey (career 1.47 WHIP).

Bryce Harper (Nationals): Harper could rip a round-tripper on Tuesday evening, when he brings his lifetime .914 OPS against right-handers (.738 vs. lefties) against Blue Jays righty Marco Estrada (career 1.4 HR/9 rate) in Game 2 of a doubleheader. The outfielder could be worth a major expenditure from DraftKings participants, having already totaled 18 homers, 43 RBIs and 42 runs across 163 at-bats this season.

Evan Longoria (Rays): During his career, the third baseman has excelled against left-handers to the tune of a .920 OPS (.813 vs. righties). Longoria could reach base often or drive in multiple runs on Tuesday, when he faces Angels southpaw C.J. Wilson (career 1.32 WHIP).

Starlin Castro (Cubs): The shortstop could improve on his lifetime .781 OPS against left-handers (.712 vs. righties) when he faces Marlins southpaw Brad Hand. The lefty hurler -- who has posted a 4.43 ERA and 1.37 WHIP in his career -- will be making just his second start of the season after being moved from the bullpen to the rotation.

Addison Russell (Cubs): In his young career, the second baseman has posted an .813 OPS against left-handers (.720 vs. righties). DraftKings participants may want to consider the touted prospect for his Tuesday game against Hand, who in his career has allowed righty batters to post a .768 OPS (.639 OPS allowed to lefty hitters).

Adam LaRoche (White Sox): The first baseman has long fared best vs. right-handers, against whom he has posted a career .842 OPS (.713 vs. lefties). On Tuesday, he could thrive against Rangers righty Colby Lewis (career 4.83 ERA), who as a Major Leaguer has allowed lefty hitters such as LaRoche to post an .833 OPS (.722 opponents' OPS vs. righty hitters).

Matt Carpenter (Cardinals): Carpenter could use his premier lineup spot to compile hits and runs for DraftKings participants when he takes his lifetime .848 OPS against right-handers (.778 vs. lefties) into a matchup with Brewers righty Tyler Cravy, who will be making his first career start after posting a 4.04 ERA with Triple-A Colorado Springs this year.

Jason Heyward (Cardinals): Having posted pronounced career splits, with an .826 OPS against right-handers that notably exceeds his .662 mark vs. lefties, the outfielder could have success vs. Cravy, who has made just 10 career appearances above Double-A. Heyward could also benefit from hitting into a Brewers defense that ranks 27th in the Majors with a .672 defensive efficiency ratio.

Freddie Freeman (Braves): On Tuesday, Freeman could show his power at homer-happy Chase Field against D-backs righty Josh Collmenter (5.05 ERA, 1.39 WHIP in 2015). During his career, the first baseman has posted an .878 OPS against right-handers that exceeds his .737 mark vs. lefties.

Nelson Cruz (Mariners): Cruz is a strong candidate to rip a round-tripper on Tuesday, when he brings his lifetime .917 OPS against left-handers (.814 vs. righties) into a matchup with Yankees southpaw CC Sabathia. The outfielder has slugged 58 homers since the start of the 2014 season, and Sabathia has surrendered 48 home runs across 50 starts since the start of the 2013 campaign.

Max Scherzer (Nationals): The right-hander is set to face the Blue Jays' lineup -- the highest-scoring in the Majors this season -- in the second game of a doubleheader on Tuesday. However, the Toronto offense has been far more effective against lefties than righties in 2015, posting the Majors' top-ranked OPS against southpaws (.876) compared to the ninth-best mark (.738) vs. righty hurlers. With a 1.51 ERA and a 0.88 WHIP this season, Scherzer has the skills to compile quality frames at his pitcher-friendly home park, and he could pick up a win in a seemingly advantageous matchup with Estrada.

Chris Archer (Rays): With a 2.12 ERA and a 0.99 WHIP, Archer is in the midst of a breakout season. On Tuesday, the right-hander could continue to excel when he faces an Angels lineup that ranks 28th in the Majors with a .658 OPS against righties. During the tilt, he could enjoy the support of a Rays defensive group that leads baseball with a .725 defensive efficiency ratio.

Johnny Cueto (Reds): Although he's coming off an extended layoff due to right elbow stiffness, Cincinnati's ace will be an appealing option for Tuesday. He will attempt to improve on his impressive 2015 stats (3.03 ERA, 0.96 WHIP) at the expense of a Phillies lineup that ranks last in the Majors in both OPS against right-handers (.613) and total runs scored (157). Cueto could emerge victorious if the Reds lineup can score several runs against O'Sullivan.

Noah Syndergaard (Mets): With a 2.55 ERA and a 1.09 WHIP, Syndergaard has excelled during his first four Major League starts. On Tuesday, the right-hander could extend his initial success when he heads to pitcher-friendly Petco Park to face a Padres lineup that ranks 26th in the Majors with a .671 OPS against righties.