Cubs Roster & Staff
Transactions
| Date | Transaction |
| 06/30/12 | Chicago Cubs signed free agent RF Jorge Soler. |
| 06/29/12 | Chicago Cubs sent RHP Randy Wells outright to Iowa Cubs. |
| 06/27/12 | Rafael Dolis roster status changed by Chicago Cubs. |
| 06/27/12 | Chicago Cubs designated Randy Wells for assignment. |
| 06/27/12 | Chicago Cubs recalled Rafael Dolis from Iowa Cubs. |
| 06/27/12 | Chicago Cubs signed free agent RHP Jesus Baldayaque to a minor league contract. |
| 06/26/12 | David Bote assigned to AZL Cubs from Chicago Cubs. |
| 06/26/12 | Chicago Cubs optioned Adrian Cardenas to Iowa Cubs. |
| 06/26/12 | Chicago Cubs recalled Anthony Rizzo from Iowa Cubs. |
| 06/25/12 | Chicago Cubs signed SS David Bote. |
| 06/24/12 | Chicago Cubs signed OF Bijan Rademacher. |
| 06/24/12 | Chicago Cubs signed free agent RHP Anthony York to a minor league contract. |
| 06/20/12 | Tim Saunders assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | LHP Anthony Prieto assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Stephen Perakslis assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Eddie Orozco assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | RHP Chad Martin assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Pierce Johnson assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Jacob Rogers assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Nathan Dorris assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Paul Blackburn assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Ben Carhart assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Joshua Conway assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Stephen Bruno assigned to Boise Hawks from Chicago Cubs. |
| 06/20/12 | Chadd Krist assigned to Boise Hawks from Chicago Cubs. |
| 06/20/12 | Lance Rymel assigned to Boise Hawks from Chicago Cubs. |
| 06/20/12 | Matt Iannazzo assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Corbin Hoffner assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Michael Heesch assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Michael Hamann assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Izaac Garsez assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Carlos Escobar assigned to AZL Cubs from Chicago Cubs. |
| 06/20/12 | Rashad Crawford assigned to AZL Cubs from Chicago Cubs. |
| 06/19/12 | Chicago Cubs signed RHP Pierce Johnson. |
| 06/19/12 | Chicago Cubs signed free agent LHP Kyle Shepard to a minor league contract. |
| 06/18/12 | Geovany Soto roster status changed by Chicago Cubs. |
| 06/18/12 | Chicago Cubs recalled Scott Maine from Iowa Cubs. |
| 06/18/12 | Chicago Cubs signed free agent LHP Matt Iannazzo to a minor league contract. |
| 06/18/12 | Chicago Cubs optioned Welington Castillo to Iowa Cubs. |
| 06/18/12 | Chicago Cubs signed RHP Michael Hamann. |
| 06/18/12 | Chicago Cubs signed LHP Anthony Prieto. |
| 06/18/12 | Chicago Cubs signed RHP Chad Martin. |
| 06/18/12 | Chicago Cubs signed RHP Eddie Orozco. |
| 06/18/12 | Chicago Cubs placed RHP Ryan Dempster on the 15-day disabled list retroactive to June 16, 2012. Tight right lat. |
| 06/16/12 | Chicago Cubs signed 3B Jacob Rogers. |
| 06/16/12 | Chicago Cubs signed C Carlos Escobar. |
| 06/16/12 | Chicago Cubs signed LHP Nathan Dorris. |
| 06/16/12 | Chicago Cubs signed 3B Ben Carhart. |
| 06/16/12 | Chicago Cubs signed SS Tim Saunders. |
| 06/16/12 | Chicago Cubs signed RHP Stephen Perakslis. |
| 06/16/12 | Chicago Cubs signed C Lance Rymel. |
| 06/16/12 | Chicago Cubs signed OF Izaac Garsez. |
| 06/16/12 | Chicago Cubs signed SS Stephen Bruno. |
| 06/16/12 | Chicago Cubs signed OF Rashad Crawford. |
| 06/16/12 | Chicago Cubs signed RHP Corbin Hoffner. |
| 06/16/12 | Chicago Cubs signed RHP Paul Blackburn. |
| 06/16/12 | Chicago Cubs signed C Chadd Krist. |
| 06/16/12 | Chicago Cubs signed LHP Michael Heesch. |
| 06/16/12 | Chicago Cubs signed RHP Joshua Conway. |
| 06/16/12 | Chicago Cubs sent Koyie Hill outright to Iowa Cubs. |
| 06/14/12 | Chicago Cubs placed 3B Ian Stewart on the 15-day disabled list retroactive to June 13, 2012. Sore left wrist. |
| 06/14/12 | Chicago Cubs selected the contract of 3B Luis Valbuena from Iowa Cubs. |
| 06/14/12 | Welington Castillo roster status changed by Chicago Cubs. |
| 06/14/12 | Chicago Cubs designated Koyie Hill for assignment. |
| 06/06/12 | Chicago Cubs placed RHP Blake Parker on the 60-day disabled list. Right elbow stress reaction. |
| 06/06/12 | Chicago Cubs selected the contract of RHP Manny Corpas from Iowa Cubs. |
| 06/05/12 | Chicago Cubs signed free agent RHP Francisco Carrillo to a minor league contract. |
| 06/05/12 | Chicago Cubs signed free agent SS Jenner Emeterio to a minor league contract. |
| 06/05/12 | Chicago Cubs signed free agent LHP Andin Diaz to a minor league contract. |
| 06/04/12 | Chicago Cubs sent Michael Bowden outright to Iowa Cubs. |
| 06/01/12 | Chicago Cubs claimed RHP Jairo Asencio off waivers from Cleveland Indians. |
| 06/01/12 | Chicago Cubs designated Michael Bowden for assignment. |
| 06/01/12 | Chicago Cubs signed free agent LHP Alfredo Belizaire to a minor league contract. |