Smyly (torn left labrum) went on the disabled list on May 9. The left-hander has made one rehab start in his pursuit to return to the Rays' rotation. He is expected to throw four innings and approximately 60 pitches on Friday.
Smyly is 0-1 with a 2.70 ERA in three starts for Tampa Bay this season. Prior to the start of the season, he was penciled in as the team's No. 3 starter, but he began the season on the DL due to left shoulder tendinitis.
Meanwhile, outfielder Desmond Jennings will return to action on Friday, beginning a rehab assignment with Triple-A Durham.
"It will be kind of like the standard DH, play, off," Cash said. "Like how we built up [John] Jaso, very similar."
Jennings played in just 18 games before going on the DL on May 3 with left knee bursitis, which eventually mandated a clean-up surgery. If all goes well, he is expected to be back with the team by mid-August.