Astros Roster & Staff
Transactions
| Date | Transaction |
| 05/27/23 | Houston Astros signed free agent RHP Francisco Frias to a minor league contract. |
| 05/23/23 | Houston Astros signed free agent RHP Porfirio Ramos to a minor league contract. |
| 05/22/23 | Houston Astros activated LHP Parker Mushinski from the 15-day injured list. |
| 05/22/23 | Houston Astros optioned LHP Matt Gage to Sugar Land Space Cowboys. |
| 05/19/23 | Houston Astros activated 2B Jose Altuve from the 10-day injured list. |
| 05/19/23 | Houston Astros optioned SS David Hensley to Sugar Land Space Cowboys. |
| 05/16/23 | Houston Astros sent 2B Jose Altuve on a rehab assignment to Corpus Christi Hooks. |
| 05/16/23 | Houston Astros sent 2B Jose Altuve on a rehab assignment to Corpus Christi Hooks. |
| 05/15/23 | Houston Astros signed free agent C Garrett Wolforth to a minor league contract. |
| 05/12/23 | Houston Astros sent 2B Jose Altuve on a rehab assignment to Sugar Land Space Cowboys. |
| 05/12/23 | Houston Astros sent 2B Jose Altuve on a rehab assignment to Sugar Land Space Cowboys. |
| 05/12/23 | Houston Astros sent 2B Jose Altuve on a rehab assignment to Sugar Land Space Cowboys. |
| 05/08/23 | Houston Astros activated RF Chas McCormick from the 10-day injured list. |
| 05/08/23 | Houston Astros optioned 3B Rylan Bannon to Sugar Land Space Cowboys. |
| 05/08/23 | Houston Astros purchased RHP Kyle McGowin from Staten Island Ferry Hawks. |
| 05/06/23 | Houston Astros optioned RHP Ronel Blanco to Sugar Land Space Cowboys. |
| 05/06/23 | Houston Astros recalled RHP J.P. France from Sugar Land Space Cowboys. |
| 05/05/23 | Philadelphia Phillies traded LHP Nick Allgeyer to Houston Astros for cash. |
| 05/02/23 | Houston Astros placed RHP Luis Garcia on the 15-day injured list. Right elbow discomfort. |
| 05/02/23 | Houston Astros recalled LHP Matt Gage from Sugar Land Space Cowboys. |
| 05/01/23 | Houston Astros transferred RHP José Urquidy from the 15-day injured list to the 60-day injured list. |
| 05/01/23 | Houston Astros placed RHP José Urquidy on the 15-day injured list. Right shoulder discomfort. |
| 05/01/23 | Houston Astros recalled RHP Brandon Bielak from Sugar Land Space Cowboys. |