Astros Roster & Staff
Transactions
| Date | Transaction |
| 12/10/25 | Houston Astros purchased contract of RHP Roddery Muñoz in the Rule 5 Draft. |
| 12/10/25 | Houston Astros purchased contract of RF Edwin Sanchez in the Rule 5 Draft, AAA Phase. |
| 12/10/25 | Athletics purchased contract of RHP Abel Mercedes in the Rule 5 Draft, AAA Phase. |
| 12/10/25 | Houston Astros purchased contract of RHP Trey McLoughlin in the Rule 5 Draft, AAA Phase. |
| 12/09/25 | Houston Astros signed free agent RHP Ryan Weiss. |
| 12/05/25 | Houston Astros sent RHP Logan VanWey outright to Sugar Land Space Cowboys. |
| 12/05/25 | Houston Astros sent LF Taylor Trammell outright to Sugar Land Space Cowboys. |
| 12/04/25 | Chicago Cubs traded RHP Nico Zeglin to Houston Astros for cash. |