Single Game Records
Club Records - Batting
| Record | Opponent | Date |
|---|---|---|
| Most runs -- 24 | Detroit | May 18, 1912 |
| Boston | May 1, 1929 | |
| Most hits, nine innings -- 29 | Boston | May 1, 1929 |
| Most hits, extra innings -- 29 (15 innings) | Texas | July 1, 1979 |
| Most triples -- 6 | Detroit | May 18, 1912 |
| Most home runs -- 8 | California | June 27, 1996 |
| Most home runs, inning -- 4 | Boston | August 21, 1997 |
| Tampa Bay | August 1, 1999 | |
| Chicago | April 27, 2002 | |
| Most total bases -- 44 | Boston | May 1, 1929 |
| California | June 27, 1996 | |
| Most strikeouts, nine innings -- 19 | Seattle | June 24, 1997 |
| Cleveland | May 30, 2017 | |
| Most strikeouts, extra innings -- 21 (15 innings) | Tampa Bay | July 30, 2012 |
Individual Records - Batting
| Record | Player | Opponent | Date |
|---|---|---|---|
| Most runs -- 5 (several times) | Last: Luis Polonia | Kansas City | September 9, 1988 |
| Most hits -- 6 | Danny Murphy | Boston | July 8, 1902 |
| Jimmie Foxx | Washington | May 30, 1930 | |
| Roger Cramer | Chicago | June 20, 1932 | |
| Jimmie Foxx | Cleveland | July 10, 1932 | |
| Bob Johnson | Chicago | June 16, 1934 | |
| Roger Cramer | Detroit | July 13, 1935 | |
| Joe DeMaestri | Detroit | July 8, 1955 | |
| Most singles -- 6 | Roger Cramer | Chicago | June 20, 1932 |
| Joe DeMaestri | Detroit | July 8, 1955 | |
| Most doubles -- 4 | Frankie Hayes | Cleveland | July 25, 1936 |
| Most triples -- 3 | Bert Campaneris | Cleveland | August 29, 1967 |
| Most home runs -- 3 (28 times) | Last: Khris Davis | Texas | May 17, 2016 |
| First rookie in MLB history with a four-homer game | Nick Kurtz | Houston | July 25, 2025 |
| Most RBIs -- 10 | Reggie Jackson | Boston | June 14, 1969 |
| Most total bases -- 16 | Jimmie Foxx | Cleveland | July 10, 1932 |
| Most walks -- 5 (several times) | Last: Mark McGwire | Kansas City | April 26, 1997 |
| Most strikeouts -- 5 (several times) | Last: Dustin Fowler | Houston | July 9, 2018 |
| Most sacrifice flies -- 2 (32 times) | Last: Stephen Vogt | Tampa Bay | May 24, 2015 |
| Most stolen bases -- 6 | Eddie Collins | Detroit | September 11, 1912 |
| Eddie Collins | St. Louis | September 22, 1912 |
Club Records - Pitching
| Record | Opponent | Date |
|---|---|---|
| Most runs allowed -- 29 | Chicago | April 23, 1955 |
| Most walks allowed -- 18 | Detroit | May 9, 1916 |
| Most home runs allowed -- 8 | New York | June 28, 1939 |
| Most wild pitches -- 5 (since 1908) | Chicago | June 7, 1937 |
| Most balks -- 5 | Seattle | April 13, 1988 |
Individual Records - Pitching
| Record | Player | Opponent | Date |
|---|---|---|---|
| Most innings pitched -- 24 | Jack Coombs | Boston | September 1, 1906 |
| Most hits allowed, nine innings -- 26 | Hod Lisenbee | Chicago | September 11, 1936 |
| Most hits allowed, extra-innings -- 29 (18 innings) | Eddie Rommel | Cleveland | July 10, 1932 |
| Most walks allowed -- 16 | Bruno Haas | New York | June 23, 1915 |
| Most strikeouts, nine innings -- 16 | Jose Rijo | Seattle | April 19, 1986 |
| Most strikeouts, extra-innings -- 18 | Jack Coombs | Boston | September 1, 1906 |
| Jack Coombs | Chicago | August 4, 1910 | |
| Most strikeouts, inning -- 4 | Blake Stein | Tampa Bay | July 27, 1998 |
| Erik Hiljus | Texas | June 30, 2001 | |
| Ryan Cook | Baltimore | April 27, 2012 | |
| Ryan Dull | Chicago-AL | April 17, 2018 | |
| Most home runs allowed -- 6 | George Caster | Boston | September 24, 1940 |