Blue Jays Roster & Staff
Transactions
| Date | Transaction |
| 04/30/22 | Toronto Blue Jays recalled RHP Bowden Francis from Buffalo Bisons. |
| 04/29/22 | Toronto Blue Jays selected the contract of SS Vinny Capra from Buffalo Bisons. |
| 04/29/22 | Toronto Blue Jays optioned RHP Bowden Francis to Buffalo Bisons. |
| 04/27/22 | Toronto Blue Jays reassigned LHP Andrew Vasquez to the minor leagues. |
| 04/27/22 | Toronto Blue Jays placed LHP Ryan Borucki on the 10-day injured list. Left middle finger blister. |
| 04/27/22 | Toronto Blue Jays activated C Tyler Heineman. |
| 04/27/22 | Toronto Blue Jays recalled LHP Andrew Vasquez from Buffalo Bisons. |
| 04/25/22 | Toronto Blue Jays placed 2B Cavan Biggio on the 10-day injured list. |
| 04/25/22 | Toronto Blue Jays recalled RHP Bowden Francis from Buffalo Bisons. |
| 04/21/22 | Toronto Blue Jays optioned LHP Anthony Kay to Buffalo Bisons. |
| 04/21/22 | Toronto Blue Jays recalled LHP Tayler Saucedo from Buffalo Bisons. |
| 04/19/22 | Toronto Blue Jays activated C Tyler Heineman. |
| 04/17/22 | Toronto Blue Jays activated LHP Ryan Borucki from the 10-day injured list. |
| 04/17/22 | Toronto Blue Jays placed LHP Hyun Jin Ryu on the 10-day injured list. Left forearm inflammation. |
| 04/15/22 | Washington Nationals claimed CF Josh Palacios off waivers from Toronto Blue Jays. |
| 04/14/22 | Toronto Blue Jays signed free agent C Stevie Berman to a minor league contract. |
| 04/14/22 | Toronto Blue Jays placed LF Teoscar Hernandez on the 10-day injured list. Left oblique strain. |
| 04/14/22 | Toronto Blue Jays recalled 2B Gosuke Katoh, and from Buffalo Bisons. |
| 04/12/22 | Toronto Blue Jays signed free agent RHP Garrett Farmer to a minor league contract. |
| 04/12/22 | Toronto Blue Jays signed free agent RHP Jake Elliott to a minor league contract. |
| 04/11/22 | Toronto Blue Jays designated CF Josh Palacios for assignment. |
| 04/11/22 | Toronto Blue Jays placed C Danny Jansen on the 10-day injured list. Left oblique strain. |
| 04/11/22 | Toronto Blue Jays activated C Tyler Heineman. |
| 04/11/22 | Toronto Blue Jays activated C Tyler Heineman. |
| 04/11/22 | Toronto Blue Jays optioned LHP Tayler Saucedo to Buffalo Bisons. |
| 04/11/22 | Toronto Blue Jays selected the contract of C Tyler Heineman from Buffalo Bisons. |
| 04/11/22 | Toronto Blue Jays recalled LHP Anthony Kay, and from Buffalo Bisons. |
| 04/10/22 | Toronto Blue Jays optioned 2B Gosuke Katoh to Buffalo Bisons. |
| 04/08/22 | Toronto Blue Jays activated CF Bradley Zimmer. |
| 04/08/22 | Toronto Blue Jays activated CF Bradley Zimmer. |
| 04/08/22 | Toronto Blue Jays activated CF Bradley Zimmer. |
| 04/08/22 | Cleveland Guardians traded CF Bradley Zimmer to Toronto Blue Jays for RHP Anthony Castro. |
| 04/08/22 | Cleveland Guardians traded CF Bradley Zimmer to Toronto Blue Jays for RHP Anthony Castro. |
| 04/07/22 | Toronto Blue Jays activated C Zack Collins. |
| 04/07/22 | Toronto Blue Jays activated C Zack Collins. |
| 04/07/22 | Toronto Blue Jays selected the contract of 2B Gosuke Katoh from New Hampshire Fisher Cats. |
| 04/07/22 | Toronto Blue Jays recalled C Zack Collins from Buffalo Bisons. |
| 04/05/22 | SS Manuel Beltre roster status changed by Toronto Blue Jays. |
| 04/05/22 | RHP Conor Larkin roster status changed by Toronto Blue Jays. |
| 04/05/22 | RHP Conor Larkin assigned to Toronto Blue Jays. |
| 04/05/22 | LHP Marc Civit roster status changed by Toronto Blue Jays. |
| 04/05/22 | SS Manuel Beltre assigned to Toronto Blue Jays. |
| 04/05/22 | LHP Marc Civit assigned to Toronto Blue Jays. |
| 04/05/22 | LHP Soenni Martinez roster status changed by Toronto Blue Jays. |
| 04/05/22 | LHP Soenni Martinez assigned to Toronto Blue Jays. |
| 04/04/22 | SS Rainer Nunez roster status changed by Toronto Blue Jays. |
| 04/04/22 | RHP Julian Valdez and assigned to Toronto Blue Jays. |
| 04/04/22 | 2B Adrian Pinto and assigned to Toronto Blue Jays. |
| 04/04/22 | LHP Braden Scott and assigned to Toronto Blue Jays. |
| 04/04/22 | SS Rainer Nunez assigned to Toronto Blue Jays. |
| 04/04/22 | RHP Ryan Boyer and assigned to Toronto Blue Jays. |
| 04/04/22 | 3B Damiano Palmegiani and assigned to Toronto Blue Jays. |
| 04/04/22 | Toronto Blue Jays optioned C Zack Collins to Buffalo Bisons. |
| 04/04/22 | Toronto Blue Jays optioned LHP Andrew Vasquez to Buffalo Bisons. |
| 04/03/22 | 3B Riley Tirotta roster status changed by Toronto Blue Jays. |
| 04/03/22 | CF Gabriel Martinez roster status changed by Toronto Blue Jays. |
| 04/03/22 | C Andres Sosa assigned to Toronto Blue Jays. |
| 04/03/22 | Toronto Blue Jays signed free agent LHP Trey Cumbie to a minor league contract. |
| 04/03/22 | C Andres Sosa roster status changed by Toronto Blue Jays. |
| 04/03/22 | CF Gabriel Martinez assigned to Toronto Blue Jays. |
| 04/03/22 | 3B Riley Tirotta assigned to Toronto Blue Jays. |
| 04/03/22 | Toronto Blue Jays traded C Reese McGuire to Chicago White Sox for C Zack Collins. |
| 04/03/22 | Toronto Blue Jays optioned RHP Anthony Castro to Buffalo Bisons. |
| 04/03/22 | Toronto Blue Jays traded C Reese McGuire to Chicago White Sox for C Zack Collins. |
| 04/02/22 | 1B PK Morris assigned to Toronto Blue Jays. |
| 04/02/22 | C Victor Mesia roster status changed by Toronto Blue Jays. |
| 04/02/22 | Toronto Blue Jays signed free agent 3B Joshua Fuentes to a minor league contract. |
| 04/02/22 | SS Jose Rivas and assigned to Toronto Blue Jays. |
| 04/02/22 | C Victor Mesia assigned to Toronto Blue Jays. |
| 04/02/22 | 1B PK Morris roster status changed by Toronto Blue Jays. |
| 04/01/22 | Toronto Blue Jays activated RHP David Phelps. |
| 04/01/22 | Toronto Blue Jays activated RHP David Phelps. |
| 04/01/22 | Toronto Blue Jays selected the contract of RHP David Phelps from Buffalo Bisons. |