Blue Jays Roster & Staff
Transactions
| Date | Transaction |
| 05/31/22 | Toronto Blue Jays designated LHP Ryan Borucki for assignment. |
| 05/31/22 | Toronto Blue Jays recalled RHP Trent Thornton from Buffalo Bisons. |
| 05/26/22 | Toronto Blue Jays sent RHP Nate Pearson on a rehab assignment to Dunedin Blue Jays. |
| 05/26/22 | Toronto Blue Jays sent RHP Nate Pearson on a rehab assignment to Dunedin Blue Jays. |
| 05/26/22 | Toronto Blue Jays reassigned SS Vinny Capra to the minor leagues. |
| 05/26/22 | Toronto Blue Jays recalled 2B Cavan Biggio, , and from Buffalo Bisons. |
| 05/26/22 | Toronto Blue Jays optioned SS Vinny Capra to Buffalo Bisons. |
| 05/24/22 | Toronto Blue Jays signed free agent RHP Eric Yardley to a minor league contract. |
| 05/24/22 | Los Angeles Dodgers traded RHP Francisco Lucumi to Toronto Blue Jays. |
| 05/23/22 | Toronto Blue Jays recalled RHP Julian Merryweather from Buffalo Bisons. |
| 05/23/22 | Toronto Blue Jays optioned C Zack Collins to Buffalo Bisons. |
| 05/16/22 | Toronto Blue Jays placed LHP Tim Mayza on the 15-day injured list retroactive to May 15, 2022. Left forearm inflammation. |
| 05/16/22 | Toronto Blue Jays optioned 2B Cavan Biggio to Buffalo Bisons. |
| 05/16/22 | Pittsburgh Pirates claimed C Tyler Heineman off waivers from Toronto Blue Jays. |
| 05/16/22 | Toronto Blue Jays recalled LHP Andrew Vasquez from Buffalo Bisons. |
| 05/14/22 | Toronto Blue Jays activated LHP Hyun Jin Ryu. |
| 05/14/22 | Toronto Blue Jays activated C Danny Jansen. |
| 05/14/22 | Toronto Blue Jays optioned C Tyler Heineman to Buffalo Bisons. |
| 05/14/22 | Toronto Blue Jays optioned RHP Trent Thornton to Buffalo Bisons. |
| 05/13/22 | Toronto Blue Jays signed free agent RHP Rafael Sanchez to a minor league contract. |
| 05/12/22 | Toronto Blue Jays signed free agent RHP Rafael Diaz to a minor league contract. |
| 05/10/22 | Toronto Blue Jays sent 2B Cavan Biggio on a rehab assignment to Buffalo Bisons. |
| 05/10/22 | Toronto Blue Jays sent C Danny Jansen on a rehab assignment to Dunedin Blue Jays. |
| 05/08/22 | Toronto Blue Jays optioned RHP Casey Lawrence to Buffalo Bisons. |
| 05/08/22 | Toronto Blue Jays selected the contract of RHP Brady Lail from High Point Rockers. |
| 05/07/22 | Toronto Blue Jays activated LF Teoscar Hernandez. |
| 05/07/22 | Toronto Blue Jays activated LHP Ryan Borucki from the 10-day injured list. |
| 05/07/22 | New York Mets claimed 2B Gosuke Katoh off waivers from Toronto Blue Jays. |
| 05/07/22 | Toronto Blue Jays optioned RHP Julian Merryweather to Buffalo Bisons. |
| 05/05/22 | Toronto Blue Jays signed free agent LHP Derek Holland to a minor league contract. |
| 05/05/22 | Toronto Blue Jays sent LHP Hyun Jin Ryu on a rehab assignment to Buffalo Bisons. |
| 05/04/22 | Toronto Blue Jays designated 2B Gosuke Katoh for assignment. |
| 05/04/22 | Toronto Blue Jays optioned LHP Andrew Vasquez to Buffalo Bisons. |
| 05/04/22 | Toronto Blue Jays selected the contract of RHP Casey Lawrence from Buffalo Bisons. |
| 05/03/22 | Toronto Blue Jays sent LF Teoscar Hernandez on a rehab assignment to Dunedin Blue Jays. |
| 05/02/22 | Toronto Blue Jays optioned 2B Gosuke Katoh to Buffalo Bisons. |
| 05/02/22 | Toronto Blue Jays optioned RHP Bowden Francis to Buffalo Bisons. |