Cubs Roster & Staff
Transactions
| Date | Transaction |
| 08/31/16 | Chicago Cubs optioned RHP Spencer Patton to Iowa Cubs. |
| 08/31/16 | Chicago Cubs recalled 3B Tommy La Stella from Iowa Cubs. |
| 08/30/16 | Chicago Cubs signed free agent SS Oswaldo Pina to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent RHP Keiber Arredondo to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent RHP Kleiber Carreno to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent RHP Denmy Sanchez to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent OF Carmelo Alfonzo to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent CF Ricardo Verenzuela to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent 3B Jeinser Brete to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent LHP Jonathan Bruzual to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent RHP Yovanny Cruz to a minor league contract. |
| 08/29/16 | Chicago Cubs signed free agent RHP Jose Gomez to a minor league contract. |
| 08/27/16 | Chicago Cubs sent RHP Joe Smith on a rehab assignment to Iowa Cubs. |
| 08/25/16 | Chicago Cubs sent OF Chris Coghlan on a rehab assignment to Iowa Cubs. |
| 08/19/16 | Chicago Cubs placed RHP Hector Rondon on the 15-day disabled list retroactive to August 17, 2016. Right triceps strain. |
| 08/19/16 | Chicago Cubs placed RHP John Lackey on the 15-day disabled list retroactive to August 15, 2016. Right shoulder strain. |
| 08/19/16 | Chicago Cubs transferred RHP Dallas Beeler from the 15-day disabled list to the 60-day disabled list. Right shoulder inflammation. |
| 08/19/16 | Chicago Cubs transferred RHP Aaron Brooks from the 15-day disabled list to the 60-day disabled list. Hip contusion. |
| 08/19/16 | Chicago Cubs selected the contract of LHP Rob Zastryzny from Iowa Cubs. |
| 08/19/16 | Chicago Cubs selected the contract of RHP Felix Pena from Iowa Cubs. |
| 08/17/16 | Chicago Cubs placed LF Chris Coghlan on the 15-day disabled list. Right rib contusion. |
| 08/17/16 | Chicago Cubs recalled Spencer Patton from Iowa Cubs. |
| 08/17/16 | Chicago Cubs placed RHP Joe Smith on the 15-day disabled list. Left hamstring strain. |
| 08/17/16 | Chicago Cubs signed free agent LHP Joe Thatcher to a minor league contract. |
| 08/16/16 | Chicago Cubs activated RHP Trevor Cahill from the 15-day disabled list. |
| 08/11/16 | Chicago Cubs placed RHP Pedro Strop on the 15-day disabled list. Left meniscus tear. |
| 08/11/16 | Chicago Cubs recalled Justin Grimm from Iowa Cubs. |
| 08/10/16 | Chicago Cubs signed free agent Josh Collmenter. |
| 08/09/16 | Chicago Cubs activated RHP Jason Hammel from the bereavement list. |
| 08/09/16 | DH Carlos Diaz assigned to Chicago Cubs. |
| 08/09/16 | Chicago Cubs optioned RHP Justin Grimm to Iowa Cubs. |
| 08/08/16 | Chicago Cubs released RHP Joe Nathan. |
| 08/08/16 | Chicago Cubs optioned RHP Justin Grimm to Iowa Cubs. |
| 08/05/16 | Chicago Cubs designated RHP Joe Nathan for assignment. |
| 08/05/16 | Chicago Cubs activated LF Jorge Soler from the 15-day disabled list. |
| 08/05/16 | Chicago Cubs signed free agent LHP Brian Matusz to a minor league contract. |
| 08/03/16 | Chicago Cubs signed free agent CF Lane Adams to a minor league contract. |
| 08/03/16 | Chicago Cubs sent LHP Brian Matusz outright to Iowa Cubs. |
| 08/03/16 | Chicago Cubs released LHP Clayton Richard. |
| 08/03/16 | Chicago Cubs placed RHP Jason Hammel on the bereavement list. |
| 08/03/16 | Chicago Cubs recalled Justin Grimm from Iowa Cubs. |
| 08/02/16 | Chicago Cubs optioned RHP Spencer Patton to Iowa Cubs. |
| 08/02/16 | Chicago Cubs activated RHP Joe Smith. |
| 08/01/16 | Los Angeles Angels traded RHP Joe Smith to Chicago Cubs for RHP Jesus Castillo. |
| 08/01/16 | Chicago Cubs recalled Spencer Patton from Iowa Cubs. |
| 08/01/16 | Chicago Cubs designated LHP Brian Matusz for assignment. |
| 08/01/16 | Los Angeles Angels traded RHP Joe Smith to Chicago Cubs for RHP Jesus Castillo. |