D-backs Roster & Staff
Transactions
| Date | Transaction |
| 05/31/25 | Arizona Diamondbacks signed RHP Tayler Scott. |
| 05/31/25 | Arizona Diamondbacks signed free agent RHP Reibert Barrera to a minor league contract. |
| 05/30/25 | Arizona Diamondbacks sent LHP Eduardo Rodriguez on a rehab assignment to ACL D-backs. |
| 05/30/25 | Arizona Diamondbacks designated LHP Joe Mantiply for assignment. |
| 05/30/25 | Arizona Diamondbacks signed free agent 3B Ildemaro Vargas. |
| 05/30/25 | Arizona Diamondbacks sent LHP Eduardo Rodriguez on a rehab assignment to ACL D-backs. |
| 05/30/25 | Arizona Diamondbacks optioned RHP Kevin Ginkel to Reno Aces. |
| 05/30/25 | Arizona Diamondbacks selected the contract of RHP Jeff Brigham from Reno Aces. |
| 05/29/25 | Arizona Diamondbacks signed free agent RHP Sean Reid-Foley to a minor league contract. |
| 05/29/25 | Arizona Diamondbacks optioned SS Jordan Lawlar to Reno Aces. |
| 05/28/25 | Arizona Diamondbacks signed free agent RHP Logan Mercado to a minor league contract. |
| 05/27/25 | Arizona Diamondbacks signed free agent 3B Nicky Lopez to a minor league contract. |
| 05/23/25 | Arizona Diamondbacks activated RHP Justin Martinez from the 15-day injured list. |
| 05/23/25 | Arizona Diamondbacks signed free agent OF Erickson Ayena to a minor league contract. |
| 05/22/25 | Arizona Diamondbacks optioned RHP Christian Montes De Oca to Reno Aces. |
| 05/20/25 | Arizona Diamondbacks sent RHP Justin Martinez on a rehab assignment to Reno Aces. |
| 05/20/25 | Arizona Diamondbacks sent RHP Justin Martinez on a rehab assignment to Reno Aces. |
| 05/19/25 | Arizona Diamondbacks signed free agent LHP Gregory Sanchez to a minor league contract. |
| 05/19/25 | Arizona Diamondbacks signed free agent RHP Luis Paredes to a minor league contract. |
| 05/18/25 | Arizona Diamondbacks released 2B Garrett Hampson. |
| 05/17/25 | Arizona Diamondbacks sent RHP Justin Martinez on a rehab assignment to ACL D-backs. |
| 05/16/25 | Arizona Diamondbacks placed LHP Eduardo Rodriguez on the 15-day injured list retroactive to May 15, 2025. Left shoulder inflammation. |
| 05/16/25 | Arizona Diamondbacks recalled RHP Scott McGough from Reno Aces. |
| 05/16/25 | Arizona Diamondbacks selected the contract of RHP Christian Montes De Oca from Reno Aces. |
| 05/15/25 | Arizona Diamondbacks signed free agent RHP Jonatan Bernal to a minor league contract. |
| 05/15/25 | Arizona Diamondbacks traded LHP José Castillo to New York Mets for cash. |
| 05/15/25 | Arizona Diamondbacks optioned LHP Joe Mantiply to Reno Aces. |
| 05/14/25 | LHP José Castillo roster status changed by Arizona Diamondbacks. |
| 05/12/25 | Arizona Diamondbacks designated LHP José Castillo for assignment. |
| 05/12/25 | Arizona Diamondbacks designated 2B Garrett Hampson for assignment. |
| 05/12/25 | Arizona Diamondbacks activated RHP Kendall Graveman from the 15-day injured list. |
| 05/12/25 | Arizona Diamondbacks recalled SS Jordan Lawlar from Reno Aces. |
| 05/10/25 | Arizona Diamondbacks optioned RHP Cristian Mena to Reno Aces. |
| 05/10/25 | Arizona Diamondbacks recalled LHP Joe Mantiply from Reno Aces. |
| 05/07/25 | Arizona Diamondbacks sent RHP Kendall Graveman on a rehab assignment to Reno Aces. |
| 05/06/25 | Arizona Diamondbacks recalled RHP Cristian Mena from Reno Aces. |
| 05/06/25 | Arizona Diamondbacks optioned LHP Tommy Henry to Reno Aces. |
| 05/05/25 | Arizona Diamondbacks signed free agent C Michael Pérez to a minor league contract. |
| 05/04/25 | Arizona Diamondbacks optioned RHP Scott McGough to Reno Aces. |
| 05/04/25 | Arizona Diamondbacks recalled LHP Tommy Henry from Reno Aces. |
| 05/03/25 | Arizona Diamondbacks sent RHP Kendall Graveman on a rehab assignment to ACL D-backs. |
| 05/02/25 | Arizona Diamondbacks activated 2B Ketel Marte from the 10-day injured list. |
| 05/02/25 | Arizona Diamondbacks optioned LF Jorge Barrosa to Reno Aces. |
| 05/01/25 | Arizona Diamondbacks placed RHP Justin Martinez on the 15-day injured list. Right shoulder inflammation. |
| 05/01/25 | Arizona Diamondbacks transferred LHP A.J. Puk from the 15-day injured list to the 60-day injured list. Left elbow inflammation. |
| 05/01/25 | Los Angeles Dodgers claimed RHP J.P. Feyereisen off waivers from Arizona Diamondbacks. |
| 05/01/25 | Arizona Diamondbacks selected the contract of LHP José Castillo from Reno Aces. |