Dodgers manager Don Mattingly said the lineup change was not a direct result of Sellers' poor defensive showing Tuesday.
"It's all the same. It was a part of what we're doing already," Mattingly said of the shortstop situation.
In the seventh inning of Tuesday's loss, Sellers made two errors that helped the Giants break a scoreless tie. His errant throw to first base allowed Joaquin Arias to reach safely. Arias later scored.
Sellers was off on a throw home later in the frame, an error that provided another run for San Francisco. Mattingly said after the game Sellers should have taken the out at first base rather than throwing home to try to get an out at the plate.
"When I came in Donnie told me I wasn't starting because he wanted to keep Uribe in the mix," Sellers said Wednesday. "He told me it wasn't about yesterday and not to worry about yesterday. I got yesterday out of the way."
Sellers started the first two games of the season with Hanley Ramirez sidelined by a torn ligament in his right thumb. The club likes Sellers for his defense, but he's struggled at the plate and is 0-for-6 with two strikeouts.
Sellers said he spent 35 minutes on Wednesday working on his swing with hitting coaches Mark McGwire and John Valentin.
"I've got to try and get right at the plate," Sellers said. "But I haven't lost confidence."
Mattingly hasn't lost confidence in Sellers either.