Pirates Roster & Staff
Transactions
| Date | Transaction |
| 05/21/25 | Pittsburgh Pirates recalled RHP Mike Burrows from Indianapolis Indians. |
| 05/21/25 | Pittsburgh Pirates optioned RHP Carmen Mlodzinski to Indianapolis Indians. |
| 05/20/25 | Pittsburgh Pirates placed RHP Colin Holderman on the 15-day injured list. Right thumb inflammation. |
| 05/20/25 | Pittsburgh Pirates placed 2B Nick Gonzales on the 60-day injured list. Non-displaced left ankle fracture. |
| 05/20/25 | Pittsburgh Pirates selected the contract of RHP Isaac Mattson from Indianapolis Indians. |
| 05/19/25 | Texas Rangers claimed CF Michael Helman off waivers from Pittsburgh Pirates. |
| 05/17/25 | Pittsburgh Pirates activated 1B Spencer Horwitz from the 10-day injured list. |
| 05/17/25 | Pittsburgh Pirates optioned 1B Matt Gorski to Indianapolis Indians. |
| 05/16/25 | Pittsburgh Pirates designated CF Michael Helman for assignment. |
| 05/16/25 | Pittsburgh Pirates sent 2B Nick Gonzales on a rehab assignment to Indianapolis Indians. |
| 05/16/25 | Pittsburgh Pirates sent 2B Nick Gonzales on a rehab assignment to Indianapolis Indians. |
| 05/16/25 | Pittsburgh Pirates selected the contract of RF Nick Solak from Indianapolis Indians. |
| 05/16/25 | Pittsburgh Pirates optioned CF Ji Hwan Bae to Indianapolis Indians. |
| 05/15/25 | Pittsburgh Pirates optioned CF Michael Helman to Indianapolis Indians. |
| 05/14/25 | Pittsburgh Pirates sent 1B Endy Rodríguez on a rehab assignment to Indianapolis Indians. |
| 05/14/25 | Pittsburgh Pirates transferred 1B Enmanuel Valdez from the 10-day injured list to the 60-day injured list. Left shoulder inflammation. |
| 05/14/25 | Pittsburgh Pirates claimed CF Michael Helman off waivers from St. Louis Cardinals. |
| 05/13/25 | Pittsburgh Pirates activated LF Tommy Pham. |
| 05/12/25 | Pittsburgh Pirates activated SS Isiah Kiner-Falefa from the 10-day injured list. |
| 05/12/25 | Pittsburgh Pirates signed free agent LHP Dariel Miguel to a minor league contract. |
| 05/12/25 | LF Tommy Pham suspended. |
| 05/12/25 | Pittsburgh Pirates optioned SS Liover Peguero to Indianapolis Indians. |
| 05/09/25 | Pittsburgh Pirates placed 1B Enmanuel Valdez on the 10-day injured list. Left shoulder inflammation. |
| 05/09/25 | Pittsburgh Pirates recalled CF Ji Hwan Bae from Indianapolis Indians. |
| 05/08/25 | Pittsburgh Pirates signed free agent C Yadier Crespo to a minor league contract. |
| 05/08/25 | Pittsburgh Pirates signed free agent RHP Angel Rosado to a minor league contract. |
| 05/07/25 | Pittsburgh Pirates signed free agent RHP Beau Burrows to a minor league contract. |
| 05/06/25 | Pittsburgh Pirates sent 1B Spencer Horwitz on a rehab assignment to Indianapolis Indians. |
| 05/06/25 | Pittsburgh Pirates sent RHP Dauri Moreta on a rehab assignment to Indianapolis Indians. |
| 05/04/25 | Pittsburgh Pirates activated RHP Dennis Santana from the bereavement list. |
| 05/04/25 | Pittsburgh Pirates optioned RHP Kyle Nicolas to Indianapolis Indians. |
| 05/03/25 | Pittsburgh Pirates transferred RHP Justin Lawrence from the 15-day injured list to the 60-day injured list. Right elbow inflammation. |
| 05/03/25 | Pittsburgh Pirates selected the contract of RHP Tanner Rainey from Indianapolis Indians. |
| 05/02/25 | Pittsburgh Pirates signed free agent RHP Juan Muniz to a minor league contract. |
| 05/02/25 | Pittsburgh Pirates recalled SS Liover Peguero from Indianapolis Indians. |
| 05/02/25 | Pittsburgh Pirates optioned RHP Hunter Stratton to Indianapolis Indians. |