Pirates Roster & Staff
Transactions
| Date | Transaction |
| 09/23/22 | C Tyler Heineman roster status changed by Pittsburgh Pirates. |
| 09/23/22 | Pittsburgh Pirates selected the contract of SS Ji-hwan Bae from Indianapolis Indians. |
| 09/22/22 | Pittsburgh Pirates placed LHP Eric Stout on the 15-day injured list. Low back discomfort. |
| 09/22/22 | Pittsburgh Pirates activated RHP David Bednar from the 15-day injured list. |
| 09/22/22 | Pittsburgh Pirates sent RHP Tyler Beede outright to Indianapolis Indians. |
| 09/18/22 | Pittsburgh Pirates placed RHP JT Brubaker on the 15-day injured list retroactive to September 16, 2022. Right arm inflammation. |
| 09/18/22 | Pittsburgh Pirates sent LHP Dillon Peters outright to Indianapolis Indians. |
| 09/18/22 | Pittsburgh Pirates recalled RHP Luis Ortiz from Indianapolis Indians. |
| 09/16/22 | Tampa Bay Rays claimed OF Bligh Madris off waivers from Pittsburgh Pirates. |
| 09/15/22 | Pittsburgh Pirates designated RHP Tyler Beede for assignment. |
| 09/15/22 | Pittsburgh Pirates designated LHP Dillon Peters for assignment. |
| 09/15/22 | Pittsburgh Pirates designated RHP Tyler Beede for assignment. |
| 09/15/22 | Pittsburgh Pirates designated RHP Tyler Beede for assignment. |
| 09/15/22 | Pittsburgh Pirates recalled LHP Eric Stout from Indianapolis Indians. |
| 09/14/22 | RHP Luis Ortiz returned to Indianapolis Indians from Pittsburgh Pirates. |
| 09/13/22 | Pittsburgh Pirates designated OF Bligh Madris for assignment. |
| 09/13/22 | Pittsburgh Pirates sent RHP David Bednar on a rehab assignment to Indianapolis Indians. |
| 09/13/22 | Pittsburgh Pirates sent RHP David Bednar on a rehab assignment to Indianapolis Indians. |
| 09/13/22 | Pittsburgh Pirates activated RHP Luis Ortiz. |
| 09/13/22 | Pittsburgh Pirates sent RHP David Bednar on a rehab assignment to Indianapolis Indians. |
| 09/13/22 | Pittsburgh Pirates optioned SS Tucupita Marcano to Indianapolis Indians. |
| 09/13/22 | Pittsburgh Pirates selected the contract of RHP Luis Ortiz from Indianapolis Indians. |
| 09/13/22 | Pittsburgh Pirates recalled C Zack Collins, and from Indianapolis Indians. |
| 09/12/22 | Pittsburgh Pirates recalled SS Diego Castillo, and from Indianapolis Indians. |
| 09/12/22 | Pittsburgh Pirates optioned SS Hoy Park to Indianapolis Indians. |
| 09/10/22 | Pittsburgh Pirates sent 2B Josh VanMeter outright to Indianapolis Indians. |
| 09/10/22 | Pittsburgh Pirates sent LHP Cam Vieaux outright to Indianapolis Indians. |
| 09/09/22 | Pittsburgh Pirates sent LHP Dillon Peters on a rehab assignment to Altoona Curve. |
| 09/09/22 | Pittsburgh Pirates sent LHP Dillon Peters on a rehab assignment to Altoona Curve. |
| 09/08/22 | LHP Eric Stout returned to Indianapolis Indians from Pittsburgh Pirates. |
| 09/07/22 | Pittsburgh Pirates designated LHP Cam Vieaux for assignment. |
| 09/07/22 | Pittsburgh Pirates activated LHP Eric Stout. |
| 09/07/22 | Pittsburgh Pirates designated 2B Josh VanMeter for assignment. |
| 09/07/22 | Pittsburgh Pirates claimed C Zack Collins off waivers from Toronto Blue Jays. |
| 09/07/22 | Pittsburgh Pirates claimed RHP Junior Fernandez off waivers from St. Louis Cardinals. |
| 09/07/22 | Pittsburgh Pirates recalled SS Hoy Park from Indianapolis Indians. |
| 09/07/22 | Pittsburgh Pirates recalled LHP Eric Stout from Indianapolis Indians. |
| 09/07/22 | Pittsburgh Pirates optioned RHP Junior Fernandez to Indianapolis Indians. |
| 09/07/22 | Pittsburgh Pirates optioned C Zack Collins to Indianapolis Indians. |
| 09/04/22 | Pittsburgh Pirates transferred RHP Colin Holderman from the 15-day injured list to the 60-day injured list. |
| 09/04/22 | Pittsburgh Pirates claimed RHP Peter Solomon off waivers from Houston Astros. |
| 09/01/22 | Pittsburgh Pirates recalled OF Cal Mitchell, and from Indianapolis Indians. |
| 09/01/22 | Pittsburgh Pirates recalled RHP Johan Oviedo, and from Indianapolis Indians. |