Cubs Roster & Staff
Transactions
| Date | Transaction |
| 05/30/25 | Chicago Cubs signed free agent RHP Wilfran Ortega to a minor league contract. |
| 05/30/25 | Chicago Cubs released RHP Julian Merryweather. |
| 05/30/25 | Chicago Cubs signed free agent RHP Noel Chirinos to a minor league contract. |
| 05/29/25 | Chicago Cubs designated RHP Brooks Kriske for assignment. |
| 05/29/25 | Chicago Cubs signed free agent LHP Génesis Cabrera. |
| 05/25/25 | Chicago Cubs selected the contract of C Reese McGuire from Iowa Cubs. |
| 05/24/25 | Chicago Cubs designated RHP Julian Merryweather for assignment. |
| 05/24/25 | Chicago Cubs selected the contract of RHP Brooks Kriske from Iowa Cubs. |
| 05/23/25 | Chicago Cubs signed free agent RHP Fleury Soriano to a minor league contract. |
| 05/23/25 | Chicago Cubs activated RHP Ryan Brasier from the 15-day injured list. |
| 05/23/25 | Chicago Cubs optioned RHP Ethan Roberts to Iowa Cubs. |
| 05/22/25 | Chicago Cubs signed free agent C Reese McGuire to a minor league contract. |
| 05/21/25 | Chicago Cubs sent RHP Tyson Miller on a rehab assignment to Iowa Cubs. |
| 05/21/25 | Chicago Cubs sent RHP Tyson Miller on a rehab assignment to Iowa Cubs. |
| 05/21/25 | Chicago Cubs sent RHP Tyson Miller on a rehab assignment to Iowa Cubs. |
| 05/21/25 | Chicago Cubs sent 3B Nicky Lopez outright to Iowa Cubs. |
| 05/20/25 | Chicago Cubs placed RHP Porter Hodge on the 15-day injured list retroactive to May 18, 2025. Left oblique strain. |
| 05/20/25 | Chicago Cubs activated LF Ian Happ from the 10-day injured list. |
| 05/20/25 | Chicago Cubs recalled RHP Ethan Roberts from Iowa Cubs. |
| 05/20/25 | Chicago Cubs optioned C Moisés Ballesteros to Iowa Cubs. |
| 05/19/25 | Chicago Cubs designated 3B Nicky Lopez for assignment. |
| 05/19/25 | Chicago Cubs recalled 2B Matt Shaw from Iowa Cubs. |
| 05/16/25 | Chicago Cubs signed free agent RHP Kenta Maeda to a minor league contract. |
| 05/13/25 | Chicago Cubs placed RHP Tyson Miller on the 60-day injured list. Left hip impingement. |
| 05/13/25 | Chicago Cubs placed LF Ian Happ on the 10-day injured list retroactive to May 10, 2025. Left oblique strain. |
| 05/13/25 | Chicago Cubs selected the contract of C Moisés Ballesteros from Iowa Cubs. |
| 05/12/25 | Chicago Cubs activated LHP Caleb Thielbar from the paternity list. |
| 05/12/25 | Chicago Cubs optioned RHP Gavin Hollowell to Iowa Cubs. |
| 05/10/25 | Chicago Cubs transferred RHP Eli Morgan from the 15-day injured list to the 60-day injured list. Right elbow impingement. |
| 05/10/25 | Chicago Cubs optioned LHP Tom Cosgrove to Iowa Cubs. |
| 05/10/25 | Chicago Cubs selected the contract of RHP Cade Horton from Iowa Cubs. |
| 05/09/25 | Chicago Cubs signed free agent RHP Tommy Romero to a minor league contract. |
| 05/09/25 | Chicago Cubs placed LHP Caleb Thielbar on the paternity list. |
| 05/09/25 | RHP Chris Flexen changed number to 77. |
| 05/09/25 | Chicago Cubs recalled LHP Tom Cosgrove from Iowa Cubs. |
| 05/08/25 | Chicago Cubs signed free agent RHP Dawson Netz to a minor league contract. |
| 05/07/25 | Chicago Cubs sent RHP Ryan Brasier on a rehab assignment to Iowa Cubs. |
| 05/07/25 | Chicago Cubs sent RHP Ryan Brasier on a rehab assignment to Iowa Cubs. |
| 05/05/25 | Chicago Cubs placed LHP Shota Imanaga on the 15-day injured list. Left hamstring strain. |
| 05/05/25 | Chicago Cubs recalled RHP Gavin Hollowell from Iowa Cubs. |