Red Sox Roster & Staff
Transactions
| Date | Transaction |
| 12/21/21 | Boston Red Sox invited non-roster RHP Zack Kelly to spring training. |
| 12/21/21 | RHP Zack Kelly roster status changed by Boston Red Sox. |
| 12/21/21 | 2B Rob Refsnyder roster status changed by Boston Red Sox. |
| 12/21/21 | Boston Red Sox signed free agent 2B Rob Refsnyder to a minor league contract and invited him to spring training. |
| 12/13/21 | Boston Red Sox signed free agent 2B Claudio Simon to a minor league contract. |
| 12/01/21 | Boston Red Sox activated CF Jackie Bradley Jr.. |
| 12/01/21 | Boston Red Sox signed free agent LHP James Paxton. |
| 12/01/21 | Boston Red Sox signed free agent LHP Rich Hill. |
| 12/01/21 | RHP Michael Feliz roster status changed by Boston Red Sox. |
| 12/01/21 | LF Christin Stewart roster status changed by Boston Red Sox. |
| 12/01/21 | Boston Red Sox activated LHP Rich Hill. |
| 12/01/21 | Boston Red Sox activated CF Jackie Bradley Jr.. |
| 12/01/21 | Boston Red Sox activated LHP Rich Hill. |
| 12/01/21 | Boston Red Sox signed free agent LF Christin Stewart to a minor league contract. |
| 12/01/21 | Boston Red Sox signed free agent RHP Michael Feliz to a minor league contract. |
| 12/01/21 | Milwaukee Brewers traded CF Jackie Bradley Jr., SS David Hamilton and 3B Alex Binelas to Boston Red Sox for RF Hunter Renfroe. |
| 12/01/21 | Milwaukee Brewers traded CF Jackie Bradley Jr., SS David Hamilton and 3B Alex Binelas to Boston Red Sox for RF Hunter Renfroe. |
| 12/01/21 | Milwaukee Brewers traded CF Jackie Bradley Jr., SS David Hamilton and 3B Alex Binelas to Boston Red Sox for RF Hunter Renfroe. |
| 12/01/21 | Milwaukee Brewers traded CF Jackie Bradley Jr., SS David Hamilton and 3B Alex Binelas to Boston Red Sox for RF Hunter Renfroe. |