Pirates Roster & Staff
Transactions
| Date | Transaction |
| 07/31/22 | Pittsburgh Pirates activated CF Bryan Reynolds from the paternity list. |
| 07/31/22 | Pittsburgh Pirates optioned SS Diego Castillo to Indianapolis Indians. |
| 07/29/22 | Pittsburgh Pirates signed SS Termarr Johnson. |
| 07/28/22 | Pittsburgh Pirates placed CF Bryan Reynolds on the paternity list. |
| 07/28/22 | Pittsburgh Pirates signed 1B Josiah Sightler. |
| 07/28/22 | Pittsburgh Pirates recalled OF Bligh Madris from Indianapolis Indians. |
| 07/27/22 | Pittsburgh Pirates signed LHP Michael Kennedy. |
| 07/27/22 | Pittsburgh Pirates signed free agent RHP Ryan Velazquez to a minor league contract. |
| 07/27/22 | Pittsburgh Pirates signed LHP Miguel Fulgencio. |
| 07/26/22 | Pittsburgh Pirates signed OF Tres Gonzalez. |
| 07/26/22 | Pittsburgh Pirates signed C Nick Cimillo. |
| 07/26/22 | Pittsburgh Pirates sent RHP Nick Mears on a rehab assignment to Bradenton Marauders. |
| 07/26/22 | Pittsburgh Pirates signed RHP Derek Diamond. |
| 07/26/22 | Pittsburgh Pirates signed RHP Mike Walsh. |
| 07/26/22 | Pittsburgh Pirates signed RHP Joshua Loeschorn. |
| 07/26/22 | Pittsburgh Pirates signed LHP Dominic Perachi. |
| 07/26/22 | Pittsburgh Pirates signed OF Tanner Tredaway. |
| 07/26/22 | Pittsburgh Pirates signed RHP Jaycob Deese. |
| 07/26/22 | Pittsburgh Pirates signed RHP J.P. Massey. |
| 07/26/22 | Pittsburgh Pirates signed RHP Elijah Birdsong. |
| 07/25/22 | Pittsburgh Pirates placed CF Jake Marisnick on the 10-day injured list. Right great toe sprain. |
| 07/25/22 | Pittsburgh Pirates activated CF Bryan Reynolds from the 10-day injured list. |
| 07/23/22 | Pittsburgh Pirates traded C Michael Perez to New York Mets for cash. |
| 07/22/22 | Pittsburgh Pirates signed LHP Cy Nielson. |
| 07/22/22 | Pittsburgh Pirates signed LHP Hunter Barco. |
| 07/22/22 | Pittsburgh Pirates designated C Michael Perez for assignment. |
| 07/22/22 | Pittsburgh Pirates activated CF Greg Allen from the 60-day injured list. |
| 07/22/22 | Pittsburgh Pirates signed RHP Thomas Harrington. |
| 07/22/22 | New York Mets traded RHP Colin Holderman to Pittsburgh Pirates. |
| 07/22/22 | Pittsburgh Pirates traded 1B Daniel Vogelbach to New York Mets. |
| 07/17/22 | Pittsburgh Pirates placed RHP Chase De Jong on the 15-day injured list. Left knee tendonitis. |
| 07/17/22 | Pittsburgh Pirates recalled RHP Bryse Wilson, and from Indianapolis Indians. |
| 07/15/22 | Pittsburgh Pirates activated C Tyler Heineman from the bereavement list. |
| 07/15/22 | Pittsburgh Pirates optioned CF Jack Suwinski to Indianapolis Indians. |
| 07/15/22 | Pittsburgh Pirates optioned C Michael Perez to Indianapolis Indians. |
| 07/15/22 | Pittsburgh Pirates recalled OF Cal Mitchell from Indianapolis Indians. |
| 07/14/22 | San Francisco Giants claimed LHP Aaron Fletcher off waivers from Pittsburgh Pirates. |
| 07/14/22 | Pittsburgh Pirates sent LHP Cam Vieaux outright to Indianapolis Indians. |
| 07/12/22 | Pittsburgh Pirates sent CF Greg Allen on a rehab assignment to Indianapolis Indians. |
| 07/12/22 | Pittsburgh Pirates activated LHP Dillon Peters. |
| 07/12/22 | Pittsburgh Pirates optioned LHP Eric Stout to Indianapolis Indians. |
| 07/11/22 | Pittsburgh Pirates designated LHP Cam Vieaux for assignment. |
| 07/11/22 | Pittsburgh Pirates placed CF Bryan Reynolds on the 10-day injured list. Right oblique strain. |
| 07/11/22 | Pittsburgh Pirates activated CF Jake Marisnick. |
| 07/11/22 | Pittsburgh Pirates sent RHP Austin Brice outright to Indianapolis Indians. |
| 07/08/22 | Pittsburgh Pirates signed free agent RHP Jackson Grounds to a minor league contract. |
| 07/08/22 | Pittsburgh Pirates activated SS Kevin Newman from the 60-day injured list. |
| 07/08/22 | Pittsburgh Pirates signed free agent RHP Jackson Grounds to a minor league contract. |
| 07/08/22 | Pittsburgh Pirates placed C Tyler Heineman on the bereavement list. |
| 07/08/22 | Pittsburgh Pirates designated LHP Aaron Fletcher for assignment. |
| 07/08/22 | Cleveland Guardians traded RHP Yohan Ramirez to Pittsburgh Pirates. |
| 07/08/22 | Pittsburgh Pirates optioned OF Bligh Madris to Indianapolis Indians. |
| 07/08/22 | Pittsburgh Pirates optioned RHP Bryse Wilson to Indianapolis Indians. |
| 07/07/22 | Pittsburgh Pirates optioned RHP Roansy Contreras to Indianapolis Indians. |
| 07/07/22 | Pittsburgh Pirates recalled LHP Eric Stout from Indianapolis Indians. |
| 07/07/22 | Pittsburgh Pirates recalled RHP Bryse Wilson from Indianapolis Indians. |
| 07/06/22 | Pittsburgh Pirates activated LHP Manny Banuelos. |
| 07/06/22 | Pittsburgh Pirates designated RHP Austin Brice for assignment. |
| 07/06/22 | Pittsburgh Pirates activated RHP Yerry De Los Santos from the 10-day injured list. |
| 07/06/22 | Pittsburgh Pirates sent CF Greg Allen on a rehab assignment to Bradenton Marauders. |
| 07/06/22 | Pittsburgh Pirates optioned LHP Cam Vieaux to Indianapolis Indians. |
| 07/05/22 | Pittsburgh Pirates activated RF Ben Gamel from the 10-day injured list. |
| 07/05/22 | Pittsburgh Pirates activated C Jason Delay. |
| 07/05/22 | Pittsburgh Pirates activated C Jason Delay. |
| 07/05/22 | Pittsburgh Pirates placed C Tyler Heineman on the paternity list. |
| 07/05/22 | Pittsburgh Pirates activated LF Yoshi Tsutsugo. |
| 07/05/22 | Pittsburgh Pirates optioned SS Hoy Park to Indianapolis Indians. |
| 07/05/22 | Pittsburgh Pirates optioned SS Tucupita Marcano to Indianapolis Indians. |
| 07/05/22 | Pittsburgh Pirates recalled C Jason Delay from Altoona Curve. |
| 07/05/22 | Tampa Bay Rays claimed SS Yu Chang off waivers from Pittsburgh Pirates. |
| 07/04/22 | Pittsburgh Pirates sent LHP Dillon Peters on a rehab assignment to Indianapolis Indians. |
| 07/03/22 | Pittsburgh Pirates placed RHP Yerry De Los Santos on the 10-day injured list. |
| 07/03/22 | Pittsburgh Pirates activated RHP Zach Thompson from the 15-day injured list. |
| 07/03/22 | Pittsburgh Pirates activated RHP Duane Underwood Jr. from the 10-day injured list. |
| 07/03/22 | Pittsburgh Pirates optioned RHP Bryse Wilson to Indianapolis Indians. |
| 07/03/22 | New York Yankees traded LHP Manny Banuelos to Pittsburgh Pirates for cash. |
| 07/02/22 | Pittsburgh Pirates optioned LHP Aaron Fletcher to Indianapolis Indians. |
| 07/02/22 | Pittsburgh Pirates recalled RHP Bryse Wilson from Indianapolis Indians. |
| 07/02/22 | Pittsburgh Pirates traded LHP Anthony Banda to Toronto Blue Jays for cash. |