D-backs Roster & Staff
Transactions
| Date | Transaction |
| 11/21/25 | RHP Taylor Rashi elected free agency. |
| 11/21/25 | LHP Tommy Henry elected free agency. |
| 11/21/25 | Arizona Diamondbacks signed free agent C James McCann. |
| 11/18/25 | Arizona Diamondbacks designated LHP Tommy Henry for assignment. |
| 11/18/25 | Arizona Diamondbacks selected the contract of RHP Dylan Ray from Reno Aces. |
| 11/18/25 | Arizona Diamondbacks selected the contract of LHP Kohl Drake from Reno Aces. |
| 11/18/25 | Arizona Diamondbacks selected the contract of SS Jose Fernandez from Amarillo Sod Poodles. |
| 11/18/25 | Arizona Diamondbacks selected the contract of LHP Mitch Bratt from Amarillo Sod Poodles. |
| 11/17/25 | Arizona Diamondbacks sent RHP Christian Montes De Oca outright to Reno Aces. |
| 11/16/25 | C Matt O'Neill roster status changed by Arizona Diamondbacks. |
| 11/16/25 | Arizona Diamondbacks signed free agent C Matt O'Neill to a minor league contract. |
| 11/13/25 | Arizona Diamondbacks signed free agent RHP Junior Fernández to a minor league contract. |
| 11/13/25 | RHP Junior Fernández roster status changed by Arizona Diamondbacks. |
| 11/13/25 | Arizona Diamondbacks signed free agent RHP Emiliano Mache to a minor league contract. |
| 11/06/25 | Arizona Diamondbacks activated RHP Corbin Burnes from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks activated RHP Justin Martinez from the 60-day injured list. |
| 11/06/25 | 2B Ildemaro Vargas elected free agency. |
| 11/06/25 | Arizona Diamondbacks activated LHP Blake Walston from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks activated RHP Christian Montes De Oca from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks activated RHP Kevin Ginkel from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks activated RHP Cristian Mena from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks activated 1B Pavin Smith from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks activated LHP Tommy Henry from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks activated LHP A.J. Puk from the 60-day injured list. |
| 11/06/25 | Arizona Diamondbacks sent RHP Austin Pope outright to Reno Aces. |
| 11/05/25 | Arizona Diamondbacks sent RHP Casey Kelly outright to Reno Aces. |
| 11/05/25 | Arizona Diamondbacks sent LHP Kyle Nelson outright to Reno Aces. |
| 11/05/25 | Arizona Diamondbacks sent RHP John Curtiss outright to Reno Aces. |
| 11/05/25 | Arizona Diamondbacks sent SS Connor Kaiser outright to Reno Aces. |
| 11/04/25 | RHP Elvin Rodríguez elected free agency. |
| 11/02/25 | LHP Jalen Beeks elected free agency. |
| 11/02/25 | RHP Zac Gallen elected free agency. |
| 11/02/25 | C James McCann elected free agency. |