| Year | Round | Opponent | Result |
|---|---|---|---|
| 2023 | AL Wild Card Series | Texas Rangers | Lost, 0-2 |
| 2022 | AL Wild Card Series | Cleveland Guardians | Lost, 0-2 |
| 2021 | AL Division Series | Boston Red Sox | Lost, 1-3 |
| 2020 | World Series | Los Angeles Dodgers | Lost, 2-4 |
| AL Championship Series | Houston Astros | Won, 4-3 | |
| AL Division Series | New York Yankees | Won, 3-2 | |
| AL Wild Card Series | Toronto Blue Jays | Won, 2-0 | |
| 2019 | AL Division Series | Houston Astros | Lost, 2-3 |
| AL Wild Card | Oakland Athletics | Won, 5-1 | |
| 2013 | AL Division Series | Boston Red Sox | Lost, 1-3 |
| AL Wild Card | Cleveland Indians | Won, 4-0 | |
| 2011 | AL Division Series | Texas Rangers | Lost, 1-3 |
| 2010 | AL Division Series | Texas Rangers | Lost, 2-3 |
| 2008 | World Series | Philadelphia Phillies | Lost, 1-4 |
| AL Championship Series | Boston Red Sox | Won, 4-3 | |
| AL Division Series | Chicago White Sox | Won, 3-1 |