Astros Roster & Staff
Transactions
| Date | Transaction |
| 08/28/10 | RHP Krishawn Holley assigned to GCL Astros from Houston Astros. |
| 08/28/10 | Houston Astros signed RHP Krishawn Holley. |
| 08/25/10 | Houston Astros optioned Matt Downs to Round Rock Express. |
| 08/25/10 | Houston Astros claimed 2B Matt Downs off waivers from San Francisco Giants. |
| 08/20/10 | Houston Astros selected the contract of Anderson Hernandez from Round Rock Express. |
| 08/20/10 | Houston Astros placed 2B Jeff Keppinger on the 15-day disabled list retroactive to August 17, 2010. Fractured left big toe. |
| 08/19/10 | OF Austin Wates assigned to GCL Astros from Houston Astros. |
| 08/19/10 | Tommy Manzella roster status changed by Houston Astros. |
| 08/19/10 | Houston Astros Traded 3B Pedro Feliz to St. Louis Cardinals and Palm Beach Cardinals Traded David Carpenter to Lancaster JetHawks. |
| 08/19/10 | Houston Astros recalled Fernando Abad from Round Rock Express. |
| 08/19/10 | Houston Astros placed RHP Matt Lindstrom on the 15-day disabled list retroactive to August 17, 2010. Back problems. |
| 08/16/10 | Houston Astros signed OF Austin Wates. |
| 08/11/10 | Rodney Quintero assigned to Greeneville Astros from Houston Astros. |
| 08/10/10 | Houston Astros signed RHP Rodney Quintero. |
| 08/09/10 | Houston Astros recalled Mark Melancon from Round Rock Express. |
| 08/09/10 | Houston Astros optioned LHP Wesley Wright to Round Rock Express. |
| 08/06/10 | Delino DeShields assigned to GCL Astros from Houston Astros. |
| 08/06/10 | Houston Astros sent Anderson Hernandez outright to Round Rock Express. |
| 08/05/10 | Houston Astros signed 2B Delino DeShields. |
| 08/03/10 | Houston Astros activated 3B Geoff Blum from the 15-day disabled list. |
| 08/03/10 | Houston Astros designated Anderson Hernandez for assignment. |
| 08/02/10 | Houston Astros activated RHP Jeff Fulchino from the 15-day disabled list. |
| 08/02/10 | Houston Astros optioned Fernando Abad to Round Rock Express. |