Astros Roster & Staff
Transactions
| Date | Transaction |
| 03/30/25 | Houston Astros sent RHP Lance McCullers Jr. on a rehab assignment to Sugar Land Space Cowboys. |
| 03/30/25 | Houston Astros sent RHP Lance McCullers Jr. on a rehab assignment to Sugar Land Space Cowboys. |
| 03/27/25 | Houston Astros placed RHP J.P. France on the 60-day injured list. Recovery from right shoulder surgery. |
| 03/27/25 | Houston Astros placed RHP Forrest Whitley on the 15-day injured list retroactive to March 24, 2025. Left knee injury. |
| 03/27/25 | Houston Astros placed RHP Kaleb Ort on the 15-day injured list retroactive to March 24, 2025. Left oblique strain. |
| 03/27/25 | Houston Astros placed RF Pedro León on the 10-day injured list retroactive to March 24, 2025. Left MCL sprain. |
| 03/27/25 | Houston Astros placed RHP Lance McCullers Jr. on the 15-day injured list retroactive to March 24, 2025. Recovery from right elbow surgery. |
| 03/27/25 | Houston Astros designated LF Cooper Hummel for assignment. |
| 03/27/25 | Houston Astros placed RHP Cristian Javier on the 15-day injured list retroactive to March 24, 2025. Recovery from Tommy John surgery. |
| 03/27/25 | Houston Astros placed RHP Luis Garcia on the 15-day injured list retroactive to March 24, 2025. Right elbow soreness. |
| 03/27/25 | Houston Astros placed LF Taylor Trammell on the 10-day injured list retroactive to March 24, 2025. Right calf strain. |
| 03/27/25 | Houston Astros recalled RHP Ryan Gusto from Sugar Land Space Cowboys. |
| 03/27/25 | Houston Astros selected the contract of LHP Steven Okert from Sugar Land Space Cowboys. |
| 03/27/25 | Houston Astros selected the contract of 3B Cam Smith from Corpus Christi Hooks. |
| 03/27/25 | Houston Astros selected the contract of RHP Rafael Montero from Sugar Land Space Cowboys. |
| 03/27/25 | Houston Astros selected the contract of 2B Brendan Rodgers from Sugar Land Space Cowboys. |
| 03/25/25 | Houston Astros released 1B Jon Singleton. |
| 03/25/25 | RHP Rhett Kouba assigned to Houston Astros. |
| 03/25/25 | Houston Astros signed free agent OF Drew Brutcher to a minor league contract. |
| 03/23/25 | C Jancel Villarroel assigned to Houston Astros. |
| 03/23/25 | OF Jose Gonzalez assigned to Houston Astros. |
| 03/22/25 | Houston Astros released LHP Jalen Beeks. |
| 03/22/25 | RHP Matthew Linskey assigned to Houston Astros. |
| 03/22/25 | Houston Astros released RF Ben Gamel. |
| 03/21/25 | OF Ethan Wagner roster status changed by Houston Astros. |
| 03/21/25 | C Walker Janek assigned to Houston Astros. |
| 03/20/25 | LHP Colby Langford assigned to Houston Astros. |
| 03/20/25 | Houston Astros optioned LHP Bennett Sousa to Sugar Land Space Cowboys. |
| 03/19/25 | RHP Hudson Leach assigned to Houston Astros. |
| 03/18/25 | Houston Astros optioned C César Salazar to Sugar Land Space Cowboys. |
| 03/18/25 | Houston Astros optioned SS Shay Whitcomb to Sugar Land Space Cowboys. |
| 03/18/25 | Houston Astros optioned RHP Nick Hernandez to Sugar Land Space Cowboys. |
| 03/15/25 | RHP Amilcar Chirinos assigned to Houston Astros. |
| 03/14/25 | RF Tyler Whitaker assigned to Houston Astros. |
| 03/13/25 | 2B Anthony Sherwin assigned to Houston Astros. |
| 03/13/25 | 3B Austin Deming assigned to Houston Astros. |
| 03/13/25 | LHP Nick Swiney assigned to Houston Astros. |
| 03/12/25 | SS Max Holy assigned to Houston Astros. |
| 03/12/25 | Houston Astros optioned LHP Colton Gordon to Sugar Land Space Cowboys. |
| 03/12/25 | Houston Astros optioned CF Kenedy Corona to Sugar Land Space Cowboys. |
| 03/10/25 | OF Lucas Spence assigned to Houston Astros. |
| 03/10/25 | 3B Ryan Johnson assigned to Houston Astros. |
| 03/10/25 | Houston Astros signed free agent LHP Jalen Beeks to a minor league contract. |
| 03/07/25 | Houston Astros optioned RHP Ryan Gusto to Sugar Land Space Cowboys. |
| 03/01/25 | RHP Tyler Guilfoil assigned to Houston Astros. |